Author

A. Hachani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

B. P. Howden· 2 shared C. J. Walsh· 2 shared R. Guerillot· 2 shared S. L. Baines· 2 shared T. P. Stinear· 2 shared A. M. Turner· 1 shared A. S. Hayes· 1 shared C. A. McDevitt· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMicrobiology

B. P. Howden

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Author profile →

2 papers

Recent·Most cited

The two-component regulator WalKR provides an essential link between cell wall homeostasis with DNA replication in Staphylococcus aureus

L. K. R. Sharkey, R. Guerillot, C. J. Walsh, A. M. Turner, J. Y. H. Lee, S. L. Neville, S. Klatt, S. L. Baines, S. J. Pidot, F. J. Rossello, T. Seeman, H. McWilliam, E. Cho, G. P. Carter, B. P. Howden, , I. R. Monk

This study identifies the WalKR two-component system in Staphylococcus aureus as a polyfunctional regulator linking cell wall homeostasis with DNA replication and other essential processes.

bioRxiv · Feb 27, 2023 · PreprintMicrobiology

A high-throughput cytotoxicity screening platform reveals agr-independent mutations in bacteraemia-associated Staphylococcus aureus that promote intracellular persistence

A. Hachani, S. G. Giulieri, R. Guerillot, C. J. Walsh, M. Herisse, Y. M. Soe, S. L. Baines, D. R. Thomas, S. D. Cheung, A. S. Hayes, H.-J. Cho, H. J. Newton, S. Pidot, R. C. Massey, B. P. Howden, T. P. Stinear

The paper develops a high-throughput platform to identify S. aureus mutations that enhance intracellular persistence and reduce cytotoxicity, revealing agr-independent pathoadaptive mutations.

bioRxiv · Dec 11, 2022Microbiology