Author

C. J. Walsh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Assay:ChIP-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

P. D. Cotter· 3 shared A. Hachani· 2 shared B. P. Howden· 2 shared C. M. Guinane· 2 shared E. Garcia-Gutierrez· 2 shared P. M. O'Connor· 2 shared R. Guerillot· 2 shared S. L. Baines· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersMicrobiology

P. D. Cotter

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The two-component regulator WalKR provides an essential link between cell wall homeostasis with DNA replication in Staphylococcus aureus

L. K. R. Sharkey, R. Guerillot, C. J. Walsh, A. M. Turner, J. Y. H. Lee, S. L. Neville, S. Klatt, S. L. Baines, S. J. Pidot, F. J. Rossello, T. Seeman, H. McWilliam, E. Cho, G. P. Carter, B. P. Howden, , I. R. Monk

This study identifies the WalKR two-component system in Staphylococcus aureus as a polyfunctional regulator linking cell wall homeostasis with DNA replication and other essential processes.

bioRxiv · Feb 27, 2023 · PreprintMicrobiology

A high-throughput cytotoxicity screening platform reveals agr-independent mutations in bacteraemia-associated Staphylococcus aureus that promote intracellular persistence

A. Hachani, S. G. Giulieri, R. Guerillot, C. J. Walsh, M. Herisse, Y. M. Soe, S. L. Baines, D. R. Thomas, S. D. Cheung, A. S. Hayes, H.-J. Cho, H. J. Newton, S. Pidot, R. C. Massey, B. P. Howden, T. P. Stinear

The paper develops a high-throughput platform to identify S. aureus mutations that enhance intracellular persistence and reduce cytotoxicity, revealing agr-independent pathoadaptive mutations.

bioRxiv · Dec 11, 2022Microbiology

Nisin G is a novel nisin variant produced by a gut-derived Streptococcus salivarius

G. W. Lawrence, E. Garcia-Gutierrez, C. J. Walsh, P. M. O'Connor, M. Begley, P. D. Cotter, C. M. Guinane

This paper identifies a novel nisin variant, nisin G, produced by a gut-derived Streptococcus salivarius strain with narrow activity against Fusobacterium nucleatum.

bioRxiv · Feb 15, 2022Microbiology

Fermented food metagenomics reveals substrate-associated differences in taxonomy, health-associated- and antibiotic resistance-determinants

J. Leech, R. Cabrera-Rubio, A. M. Walsh, G. Macori, C. J. Walsh, W. Barton, L. Finnegan, F. Crispie, O. O'Sullivan, M. J. Claesson, P. D. Cotter

This study uses shotgun metagenomics to analyze 58 fermented foods, revealing microbial composition, functional potential, and health-associated gene clusters across different food types.

mSystems · Dec 22, 2020Peer-reviewedMicrobiology

First evidence of production of the lantibiotic nisin P

E. Garcia-Gutierrez, P. M. O'Connor, G. Saalbach, C. J. Walsh, J. W. Hegarty, C. M. Guinane, M. J. Mayer, A. Narbad, P. D. Cotter

The paper identifies a human fecal isolate producing nisin P, confirms its structure, and compares its antimicrobial activity to nisin A and H.

bioRxiv · Nov 1, 2019Microbiology