Author

J. Y. H. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

B. P. Howden· 3 shared I. R. Monk· 3 shared S. J. Pidot· 3 shared T. P. Stinear· 3 shared C. A. McDevitt· 2 shared G. P. Carter· 2 shared R. Guerillot· 2 shared T. Seemann· 2 shared

Activity by Year

2016-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersMicrobiology

B. P. Howden

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintFeb 27, 2023

The two-component regulator WalKR provides an essential link between cell wall homeostasis with DNA replication in Staphylococcus aureus

L. K. R. Sharkey, R. Guerillot, C. J. Walsh…·I. R. Monk

This study identifies the WalKR two-component system in Staphylococcus aureus as a polyfunctional regulator linking cell wall homeostasis with DNA replication and other essential processes.

DOI 10.1101/2023.02.27.530350

humanChIP-seq

𝕏 PostBluesky

MicrobiologybioRxivAug 31, 2018

Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureus

I. R. Monk, N. Shaikh, S. L. Begg…·T. P. Stinear

The paper identifies zinc binding to the WalK histidine kinase's PAS domain as a negative regulator of the WalKR two-component system in Staphylococcus aureus.

DOI 10.1038/s41467-019-10932-4

bacteria (other)experimental assay

𝕏 PostBluesky

MicrobiologybioRxivMay 16, 2016

Increasing tolerance of hospital Enterococcus faecium to hand-wash alcohols

S. J. Pidot, W. Gao, A. H. Buultjens…·T. P. Stinear

The paper shows hospital Enterococcus faecium isolates from 2010 onward are 10-fold more tolerant to alcohol-based disinfectants than older isolates, leading to increased gastrointestinal colonization in mice.

DOI 10.1126/scitranslmed.aar6115

mouseDNA methylation

𝕏 PostBluesky