Author

A. I. Kuehne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 1 Organism:human· 1 Organism:mouse· 1 Organism:non-human primate· 1 Assay:proteomics· 1

Frequent Co-Authors

A. S. Herbert· 3 shared J. M. Dye· 3 shared K. Chandran· 2 shared R. R. Bakken· 2 shared S. R. Monticelli· 2 shared A. Ghosh· 1 shared A. K. Mishra· 1 shared A. M. Moreau· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersImmunology

A. S. Herbert

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Crimean-Congo Hemorrhagic Fever Survivors Elicit Protective Non-Neutralizing Antibodies that Target 11 Overlapping Regions on Viral Glycoprotein GP38

O. S. Shin, S. R. Monticelli, C. K. Hjorth, V. Hornet, M. Doyle, D. Abelson, A. I. Kuehne, A. Wang, R. R. Bakken, A. K. Mishra, M. Middlecamp, E. Champney, L. Stuart, D. P. Maurer, J. Li, , J. S. McLellan

The paper identifies non-neutralizing antibodies from CCHFV survivors that target multiple regions on GP38, showing protective efficacy in rodent models.

bioRxiv · Mar 2, 2024Immunology

Two point mutations in protocadherin-1 disrupt Andes hantavirus recognition and afford protection against lethal infection

M. M. Slough, R. Li, A. S. Herbert, G. Lasso, A. I. Kuehne, R. R. Bakken, S. R. Monticelli, Y. Liu, A. Ghosh, A. M. Moreau, X. Zeng, S. C. Almo, J. M. Dye, R. K. Jangra, Z. Wang, K. Chandran

The paper identifies two point mutations in PCDH1 that disrupt ANDV recognition and protect against lethal infection in Syrian hamsters.

bioRxiv · Jul 19, 2022Microbiology

Animal Model Prescreening: Pre-exposure to SARS-CoV-2 impacts responses in the NHP model

K. M. Ricks, A. S. Herbert, J. W. Koehler, P. A. Kuehnert, T. L. Clements, C. J. Shoemaker, A. I. Kuehne, C. M. O'Brien, S. R. Coyne, K. L. Delp, K. S. Akers, J. M. Dye, J. W. Hooper, J. M. Smith, J. R. Kugelman, , T. D. Minogue

This study shows pre-exposure to SARS-CoV-2 affects biomarker responses in animal models, emphasizing the need for pre-screening protocols in medical countermeasure studies.

bioRxiv · Jul 6, 2020 · PreprintImmunology