Author

J. W. Hooper

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Research Focus:drug response / drug discovery· 4 Organism:non-human primate· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:human· 1

Frequent Co-Authors

A. Jay· 2 shared J. M. Smith· 2 shared K. M. Ricks· 2 shared S. A. Kwilas· 2 shared S. C. Johnston· 2 shared T. L. Clements· 2 shared A Nalca· 1 shared A. Anderson· 1 shared

Activity by Year

2020-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersImmunology

A. Jay

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A monkeypox mRNA-lipid nanoparticle vaccine targeting virus binding, entry, and transmission drives protection against lethal orthopoxviral challenge

A. W. Freyn, C. Atyeo, P. L. Earl, J. L. Americo, G.-Y. Chuang, H. Natarajan, T. R. Frey, J. Gall, J. I. Moliva, R. Hunegnaw, G. Asthagiri Arunkumar, C. Ogega, A. Nasir, H. Bennett, J. Johnson, , B. Moss

This paper develops an mRNA-lipid nanoparticle vaccine targeting four conserved MPXV surface proteins, showing superior protection against VACV compared to MVA.

bioRxiv · Dec 17, 2022 · PreprintImmunology

Humoral immunogenicity of a Coronavirus Disease 2019 (COVID-19) DNA Vaccine in Rhesus Macaques (Macaca mulatta) Delivered using Needle-free Jet Injection

A. Jay, S. A. Kwilas, M. Josleyn, K. Ricks, J. W. Hooper

This study evaluates a DNA vaccine against SARS-CoV-2 in rhesus macaques using needle-free jet injection, showing neutralizing antibody responses with intramuscular delivery but not intradermal.

bioRxiv · Sep 12, 2022 · PreprintImmunology

Antigenic mapping and functional characterization of human New World hantavirus neutralizing antibodies

T. B. Engdahl, E. Binshtein, R. L. Brocato, N. A. A. Kuzmina, L. M. Principe, S. A. Kwilas, R. K. Kim, N. S. Chapman, M. S. Porter, P. Guardado-Calvo, F. A. Rey, L. S. Handal, S. M. Diaz, I. A. Zagol-Ikapitte, J. X. Reidy, , J. E. Crowe

This study maps antigenic sites and characterizes neutralizing antibodies against hantaviruses, identifying mechanisms and cross-protective potential for vaccine development.

bioRxiv · Jul 19, 2022Immunology

A SARS-CoV-2 Spike Ferritin Nanoparticle Vaccine is Protective and Promotes a Strong Immunological Response in the Cynomolgus Macaque Coronavirus Disease 2019 (COVID-19) Model

S. C. Johnston, K. M. Ricks, I. Lakhal-Naouar, A. Jay, C. Subra, J. L. Raymond, H. A. D. King, F. Rossi, T. L. Clements, D. Fetterer, S. Tostenson, C. M. Cincotta, H. R. Hack, C. Kuklis, S. Soman, , A Nalca

This study evaluates a SARS-CoV-2 Spike ferritin nanoparticle vaccine in cynomolgus macaques, showing strong immunological responses and protection against infection.

bioRxiv · Mar 25, 2022Microbiology

Animal Model Prescreening: Pre-exposure to SARS-CoV-2 impacts responses in the NHP model

K. M. Ricks, A. S. Herbert, J. W. Koehler, P. A. Kuehnert, T. L. Clements, C. J. Shoemaker, A. I. Kuehne, C. M. O'Brien, S. R. Coyne, K. L. Delp, K. S. Akers, J. M. Dye, J. W. Hooper, J. M. Smith, J. R. Kugelman, , T. D. Minogue

This study shows pre-exposure to SARS-CoV-2 affects biomarker responses in animal models, emphasizing the need for pre-screening protocols in medical countermeasure studies.

bioRxiv · Jul 6, 2020 · PreprintImmunology