Beyond Shielding: The Roles of Glycans in SARS-CoV-2 Spike Protein
L. Casalino, Z. Gaieb, J. Goldsmith, C. K. Hjorth, A. C. Dommer, A. M. Harbison, C. A. Fogarty, E. P. Barros, B. C. Taylor, J. S. McLellan, E. Fadda, R. E. Amaro
This study reveals the structural role of glycans in modulating SARS-CoV-2 spike protein conformational dynamics and ACE2 binding through molecular simulations and experiments.
bioRxiv · Jun 11, 2020Biophysics