Author

A. T. Brunger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

L. Esquivies· 2 shared A. J. B. Kreutzberger· 1 shared A. Orr· 1 shared B. Czako· 1 shared B. Dickey· 1 shared C. A. Doyle· 1 shared C. Wang· 1 shared G. Balistreri· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

L. Esquivies

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the pre-hairpin intermediate of the spike protein

K. Yang, C. Wang, A. J. B. Kreutzberger, R. Ojha, S. Kuivanen, S. Couoh-Cardel, S. Muratcioglu, T. J. Eisen, K. I. White, R. G. Held, S. Subramanian, K. Marcus, R. A. Pfuetzner, L. Esquivies, C. A. Doyle, , A. T. Brunger

bioRxiv · Aug 11, 2022Microbiology

Screening of hydrocarbon-stapled peptides for inhibition of calcium-triggered exocytosis

Y. Lai, M. Tuvim, J. Leitz, J. J. Peters, R. Pfuetzner, L. Esquivies, Q. Zhou, B. Czako, J. Cross, P. Jones, B. Dickey, A. T. Brunger

The paper screens hydrocarbon-stapled peptides targeting the SNARE-Syt1 primary interface to inhibit Ca2+-triggered exocytosis and mucus hypersecretion.

bioRxiv · Mar 21, 2022Pharmacology & Toxicology

Sec17/Sec18 can support membrane fusion without help from completion of SNARE zippering

H. Song, T. L. Torng, A. Orr, A. T. Brunger, W. T. Wickner

The paper shows Sec17/Sec18 can drive membrane fusion independently of SNARE zippering completion.

bioRxiv · Feb 16, 2021Biochemistry

Conformational dynamics of auto-inhibition in the ER calcium sensor STIM1

S. van Dorp, R. Qiu, U. B. Choi, M. M. Wu, M. Yen, M. Kirmiz, A. T. Brunger, R. S. Lewis

This study investigates the structural dynamics of STIM1's auto-inhibition mechanism using smFRET and crosslinking, revealing how CC1 interacts with CAD to regulate SOCE.

bioRxiv · Dec 17, 2020Biophysics