Author

A. J. Groffen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:electrophysiology· 1 Organism:mouse· 1

Frequent Co-Authors

E. Kerklingh· 1 shared E. Logtenberg· 1 shared G. Brand· 1 shared G. J. L. Wuite· 1 shared J. Rizo· 1 shared M. Marchetti· 1 shared M. Piontek· 1 shared M. Verhage· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiophysics

E. Kerklingh

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2 papers

Recent·Most cited

Synaptotagmin-1 and Doc2b exhibit distinct membrane remodeling mechanisms

R. Sorkin, M. Marchetti, E. Logtenberg, M. Piontek, E. Kerklingh, G. Brand, R. Voleti, J. Rizo, W. H. Roos, A. J. Groffen, G. J. L. Wuite

This study compares how Synaptotagmin-1 and Doc2b remodel membranes through different mechanisms, revealing distinct roles in Ca2+-triggered secretion.

bioRxiv · Feb 1, 2019Biophysics

Doc2b Ca2+-binding site mutants act as a gain of function at rest and loss of function during neuronal activity

Q. Bourgeois-Jaarsma, M. Verhage, A. J. Groffen

bioRxiv · Jan 31, 2019 · PreprintCell Biology