R. Sorkin

Migrasome formation is initiated preferentially in tubular junctions by alternations of membrane tension or intracellular pressure

The paper investigates how migrasomes form preferentially in tubular junctions by altering membrane tension or intracellular pressure, using experimental and theoretical approaches.

Probing Local Force Propagation in Tensed Fibrous Gels

This study measures force propagation in tensed fibrin hydrogels and shows that force transmission becomes anisotropic with stronger response perpendicular to tension.

Tetraspanin 4 mediates migrasome formation via a two-stage mechanism

This study investigates how tetraspanin 4 mediates migrasome formation through a two-stage mechanism involving membrane tension and cholesterol.

Transmembrane proteins tetraspanin 4 and CD9 sense membrane curvature

This study shows that tetraspanin4 and CD9 sense positive membrane curvature, revealing their role in membrane shaping processes like migrasome formation and oocyte microvilli shaping.

Live cell single molecule tracking and localization microscopy of bioorthogonally labeled plasma membrane proteins

The paper demonstrates the use of genetic code expansion and bioorthogonal chemistry for live-cell single molecule tracking and localization microscopy of plasma membrane proteins, showing improved resolution and dynamics analysis.

Synaptotagmin-1 and Doc2b exhibit distinct membrane remodeling mechanisms

This study compares how Synaptotagmin-1 and Doc2b remodel membranes through different mechanisms, revealing distinct roles in Ca2+-triggered secretion.

The fluid membrane determines mechanics of red blood cell extracellular vesicles and is softened in hereditary spherocytosis

This study uses atomic force microscopy to analyze the mechanical properties of red blood cell extracellular vesicles from healthy individuals and a hereditary spherocytosis patient, finding that vesicles have a lower bending modulus in the disease state.