Author

G. J. L. Wuite

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:E. coli· 1 Assay:electrophysiology· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

M. Marchetti· 3 shared W. H. Roos· 3 shared E. J. G. Peterman· 2 shared A. Chakraborty· 1 shared A. Hernandez Garcia· 1 shared A. J. Groffen· 1 shared A. M. Malinowska· 1 shared A. Mazumder· 1 shared

Activity by Year

2018-2019 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersBiophysics

M. Marchetti

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Author profile →

4 papers

Recent·Most cited

Supercoiling DNA optically

G. A. King, F. Burla, E. J. G. Peterman, G. J. L. Wuite

This paper introduces a single-molecule assay using dual-trap optical tweezers to rapidly generate and study negatively supercoiled DNA with force spectroscopy and fluorescence imaging.

bioRxiv · Apr 26, 2019Biophysics

Synaptotagmin-1 and Doc2b exhibit distinct membrane remodeling mechanisms

R. Sorkin, M. Marchetti, E. Logtenberg, M. Piontek, E. Kerklingh, G. Brand, R. Voleti, J. Rizo, W. H. Roos, A. J. Groffen, G. J. L. Wuite

This study compares how Synaptotagmin-1 and Doc2b remodel membranes through different mechanisms, revealing distinct roles in Ca2+-triggered secretion.

bioRxiv · Feb 1, 2019Biophysics

Real-time assembly of an artificial virus elucidated at the single-particle level

M. Marchetti, D. Kamsma, E. Cazares Vargas, A. Hernandez Garcia, P. van der Schoot, R. de Vries, G. J. L. Wuite, W. H. Roos

This study uses single-molecule techniques to track real-time assembly of artificial virus-like particles, revealing nucleation and DNA packaging mechanisms.

bioRxiv · Jan 22, 2019Biophysics

One-dimensional sliding assists σ70-dependent promoter binding by Escherichia coli RNA polymerase

I. Heller, M. Marchetti, A. Mazumder, A. Chakraborty, A. M. Malinowska, W. H. Roos, R. H. Ebright, E. J. G. Peterman, G. J. L. Wuite

This study uses single-molecule imaging to show Escherichia coli RNA polymerase σ70 holoenzyme performs one-dimensional sliding on DNA during promoter search, even at high RNAP concentrations.

bioRxiv · Dec 13, 2018 · PreprintBiophysics