Author

A. J. Lay

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. L. Coppage· 1 shared B. Yau· 1 shared C. Aponte-Santamaria· 1 shared D. Butera· 1 shared D. M. Maag· 1 shared D. M.-T. Yu· 1 shared F. Graeter· 1 shared F. Kutzki· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperPathology

A. L. Coppage

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Author profile →

2 papers

Recent·Most cited

Dynamic Disulfide Bond Topologies in von-Willebrand-Factor's C4-Domain Undermine Platelet Binding

F. Kutzki, D. Butera, A. J. Lay, D. M. Maag, J. Chiu, H.-G. Woon, T. Kubar, M. Elstner, C. Aponte-Santamaria, P. Hogg, F. Graeter

This study quantifies disulfide bond topologies in vWF-C4 domain and shows their impact on platelet binding through integrin.

bioRxiv · Aug 20, 2022 · PreprintBiophysics

Fibroblast activation protein enzyme deficiency prevents liver steatosis, insulin resistance and glucose intolerance and increases fibroblast growth factor-21 in diet induced obese mice

S. Chowdhury, S. Song, H. E. Zhang, X. M. Wang, M. G. Gall, D. M.-T. Yu, A. J. Lay, M. S.-W. Xiang, K. A. Evans, S. Wetzel, Y. Liu, B. Yau, A. L. Coppage, L. Lo, R. A. Stokes, , M. D. Gorrell

This study shows that FAP deficiency in diet-induced obese mice reduces liver steatosis, insulin resistance, and glucose intolerance while increasing FGF-21 levels.

bioRxiv · Nov 4, 2018 · PreprintPathology