Author

H. E. Zhang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

G. W. McCaughan· 2 shared M. D. Gorrell· 2 shared M. G. Gall· 2 shared A. Cook· 1 shared A. J. Lay· 1 shared A. L. Coppage· 1 shared B. Roediger· 1 shared B. Yau· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersPathology

G. W. McCaughan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Phage-Assisted, Active Site-Directed Ligand Evolution with a Genetically Encoded Nε-Butyryl-ʟ-Lysine to Identify a Cellularly Potent and Selective Inhibitor for the ENL YEATS Domain as an Anti-Leukemia Agent

P.-H. C. Chen, X. S. Guo, H. E. Zhang, Z. Z. Geng, G. K. Dubey, C. A. Fierke, S. Xu, W. R. Liu

This study develops a phage-assisted ligand evolution method to identify potent ENL inhibitors, finding a pentapeptide with sub-nanomolar affinity and anti-leukemia activity.

bioRxiv · Jan 8, 2023 · PreprintBiochemistry

Fibroblast activation protein enzyme deficiency prevents liver steatosis, insulin resistance and glucose intolerance and increases fibroblast growth factor-21 in diet induced obese mice

S. Chowdhury, S. Song, H. E. Zhang, X. M. Wang, M. G. Gall, D. M.-T. Yu, A. J. Lay, M. S.-W. Xiang, K. A. Evans, S. Wetzel, Y. Liu, B. Yau, A. L. Coppage, L. Lo, R. A. Stokes, , M. D. Gorrell

This study shows that FAP deficiency in diet-induced obese mice reduces liver steatosis, insulin resistance, and glucose intolerance while increasing FGF-21 levels.

bioRxiv · Nov 4, 2018 · PreprintPathology

Immune regeneration in irradiated mice is not impaired by the absence of DPP9 enzymatic activity

M. G. Gall, H. E. Zhang, A. Cook, C. J. Jolly, G. W. McCaughan, B. Roediger, M. D. Gorrell

This study shows that DPP9 enzymatic activity is not required for immune regeneration in irradiated mice, as hematopoietic stem cell engraftment and reconstitution remain unaffected.

bioRxiv · Oct 1, 2018Immunology