Author

A. J. Wilkinson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1

Frequent Co-Authors

F. Calderon· 2 shared J. C. Mottram· 2 shared N. G. Jones· 2 shared R. Gabarro· 2 shared C. N. Russell· 1 shared G. Moore· 1 shared I. Rioja· 1 shared J. B. T. Carnielli· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBiochemistry

F. Calderon

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2 papers

Recent·Most cited

Bromodomain Factor 5 as a Target for Antileishmanial Drug Discovery

C. N. Russell, J. L. Carter, J. M. Borgia, J. Bush, F. Calderon, R. Gabarro, S. J. Conway, J. C. Mottram, A. J. Wilkinson, N. G. Jones

This paper identifies LdBDF5 as a potential drug target for antileishmanial therapy by showing its interaction with human bromodomain inhibitors and demonstrating antipromastigote activity of SGC-CBP30.

bioRxiv · Aug 21, 2023Biochemistry

Bromodomain factor 5 is an essential transcriptional regulator of the Leishmania genome.

N. G. Jones, V. Geoghegan, G. Moore, J. B. T. Carnielli, K. Newling, F. Calderon, R. Gabarro, J. Martin, R. Prinjha, I. Rioja, A. J. Wilkinson, J. C. Mottram

This study identifies BDF5 as essential for Leishmania gene expression and survival by analyzing its role in chromatin interpretation and transcriptional regulation.

bioRxiv · Sep 29, 2021Cell Biology