Author

J. Bush

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Plant Biology· 2 Bioengineering· 1 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:Arabidopsis· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:imaging· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

C. H. Haney· 3 shared F. M. Ausubel· 2 shared Y. Song· 2 shared A. Briggs· 1 shared A. C. Diener· 1 shared A. J. Powell· 1 shared A. J. Wilkinson· 1 shared A. Socha· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersPlant Biology

C. H. Haney

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Author profile →

7 papers

Recent·Most cited

mRNA display in cell lysates enables identification of cyclic peptides targeting the BRD3 extraterminal domain

C. A. Hurd, J. Bush, A. J. Powell, L. J. Walport

The paper describes a method to identify cyclic peptides targeting the BRD3 extraterminal domain using mRNA display in cell lysates, expanding the scope of target proteins for screening.

bioRxiv · Mar 20, 2024Biochemistry

Bromodomain Factor 5 as a Target for Antileishmanial Drug Discovery

C. N. Russell, J. L. Carter, J. M. Borgia, J. Bush, F. Calderon, R. Gabarro, S. J. Conway, J. C. Mottram, A. J. Wilkinson, N. G. Jones

This paper identifies LdBDF5 as a potential drug target for antileishmanial therapy by showing its interaction with human bromodomain inhibitors and demonstrating antipromastigote activity of SGC-CBP30.

bioRxiv · Aug 21, 2023Biochemistry

α-Catenin Dependent E-cadherin Adhesion Dynamics as Revealed by an Accelerated Force Ramp

J. Bush, J. I. Cabe, D. Conway, V. Maruthamuthu

This study investigates the relationship between E-cadherin adhesion strength and mobility using magnetic pulling cytometry, revealing a direct correlation and the role of α-catenin in regulating these dynamics.

bioRxiv · Jul 28, 2023Biophysics

Size-tunable ICG-based contrast agent platform for targeted near-infrared photoacoustic imaging

S. Singh, G. Giammanco, C.-H. Hu, J. Bush, L. S. Cordova, D. J. Lawrence, J. L. Moran, P. V. Chitnis, R. Veneziano

This paper develops a size-tunable ICG-based contrast agent for NIR-PAI, showing enhanced in vivo imaging of liver and spleen with high photostability and targeting ability.

bioRxiv · Sep 1, 2022Bioengineering

A screen for mutants deficient in coronatine-mediated suppression of root immunity identifies Arabidopsis SDA1 as a novel integrator of immunity and phytohormone signaling

Y. Song, X.-C. Zhang, Y. Qiu, A. Briggs, Y. Millet, D. Bartenstein, C. Mankiw, M. L. Cerulli, J. Bush, K. L. Adams, A. C. Diener, F. M. Ausubel, C. H. Haney

This study identifies Arabidopsis SDA1 as a novel negative regulator of root and leaf immunity through a genetic screen for mutants impaired in coronatine-mediated suppression of root immunity.

bioRxiv · Sep 12, 2021 · PreprintPlant Biology

Natural variation in Arabidopsis ISR1 affects iron localization and induced systemic resistance

A. Socha, Y. Song, B. Ross, J. Bush, F. M. Ausubel, M. L. Guerinot, C. H. Haney

The paper identifies ISR1 as a gene affecting iron localization and induced systemic resistance in Arabidopsis, showing its role in immunity and ROS production.

bioRxiv · Sep 1, 2021 · PreprintPlant Biology

A genome-wide screen identifies genes in rhizosphere-associated Pseudomonas required to evade plant defenses

Z. Liu, P. Beskrovnaya, R. A. Melnyk, S. S. Hossain, S. Khorasani, L. R. O'Sullivan, C. L. Wiesmann, J. Bush, J. D. Richard, C. H. Haney

This paper identifies bacterial genes in Pseudomonas sp. WCS365 that enhance rhizosphere fitness and evade Arabidopsis plant defenses through biofilm formation and immune response modulation.

bioRxiv · Jul 24, 2018Microbiology