Author

V. Geoghegan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Assay:proteomics· 2 Organism:Arabidopsis· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

J. C. Mottram· 4 shared E. Brown· 2 shared K. Newling· 2 shared N. G. Jones· 2 shared Y. R. Nievas· 2 shared A. Damianou· 1 shared A. Dowle· 1 shared A. J. Wilkinson· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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4 shared papersCell Biology

J. C. Mottram

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

TORC1 is an essential regulator of nutrient-dependent differentiation in Leishmania

E. Myburgh, V. Geoghegan, E. V. C. Alves-Ferreira, Y. R. Nievas, J. S. Grewal, E. Brown, K. McLuskey, J. C. Mottram

This study identifies TORC1 as essential for nutrient-dependent differentiation in Leishmania, showing its role in both promastigote and amastigote stages.

bioRxiv · Oct 20, 2022 · PreprintCell Biology

Bromodomain factor 5 is an essential transcriptional regulator of the Leishmania genome.

N. G. Jones, V. Geoghegan, G. Moore, J. B. T. Carnielli, K. Newling, F. Calderon, R. Gabarro, J. Martin, R. Prinjha, I. Rioja, A. J. Wilkinson, J. C. Mottram

This study identifies BDF5 as essential for Leishmania gene expression and survival by analyzing its role in chromatin interpretation and transcriptional regulation.

bioRxiv · Sep 29, 2021Cell Biology

Wolbachia strain wAu differs in cellular perturbation and virus inhibition profiles from previously characterised Wolbachia strains

S. Rainey, V. Geoghegan, D. Lefteri, T. Ant, J. Martinez, C. McNamara, S. P. Sinkins

This study compares the cellular perturbation and antiviral profiles of Wolbachia strain wAu with other strains, finding unique features in its virus inhibition mechanisms.

bioRxiv · Sep 2, 2021 · PreprintMicrobiology

Protein kinase signalling at the Leishmania kinetochore captured by XL-BioID

V. Geoghegan, N. G. Jones, A. Dowle, J. C. Mottram

The paper develops XL-BioID to study kinase signaling at the Leishmania kinetochore, identifying a novel protein and characterizing phosphosites during the cell cycle.

bioRxiv · Jul 8, 2021 · PreprintBiochemistry

Essential roles for deubiquitination in Leishmania life cycle progression

A. Damianou, R. J. Burge, C. Catta-Preta, V. Geoghegan, Y. R. Nievas, K. Newling, E. Brown, R. Burchmore, B. Rodenko, J. C. Mottram

This study identifies essential deubiquitinating enzymes (DUBs) in Leishmania life cycle progression and demonstrates their critical role in differentiation and intracellular survival.

PLOS Pathogens · Jun 16, 2020Peer-reviewedMicrobiology