Author

A. Jenney

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:whole-genome sequencing· 3 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Approach:comparative / phylogenetic analysis· 1

Frequent Co-Authors

K. E. Holt· 2 shared K. L. Wyres· 2 shared L. M. Judd· 2 shared M. M. C. Lam· 2 shared R. R. Wick· 2 shared S. Duchene· 2 shared A. Getahun Strobel· 1 shared A. J. Hayes· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMicrobiology

K. E. Holt

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Genetic heterogeneity in the Salmonella Typhi Vi capsule locus: A population genomic study from Fiji

A. Getahun Strobel, A. J. Hayes, W. Wirth, M. Mua, T. Saumalua, O. Cabenatabua, V. Soqo, V. Rosa, N. Wang, J. A. Lacey, D. Hocking, M. Valcanis, A. Jenney, B. P. Howden, S. Duchene, , M. R. Davies

This study examines genetic diversity in the Vi capsule locus of Salmonella Typhi in Fiji, identifying convergent evolution of tviE mutations globally and highlighting the need for further functional analysis.

bioRxiv · Dec 4, 2023 · PreprintMicrobiology

Combined inhibition of mTOR and PIKKs exploits replicative and checkpoint vulnerabilities to induce death of PI3K-activated triple-negative breast cancer cells

S. S. Chopra, A. Jenney, A. Palmer, M. Niepel, M. Chung, C. Mills, S. C. Sivakumaren, Q. Liu, J.-Y. Chen, C. Yapp, J. Asara, N. S. Gray, P. K. Sorger

The paper shows that combining mTOR and PIKK inhibitors kills triple-negative breast cancer cells by exploiting replication and checkpoint vulnerabilities.

bioRxiv · Jul 12, 2019 · PreprintCancer Biology

Distinct evolutionary dynamics of horizontal gene transfer in drug resistant and virulent clones of Klebsiella pneumoniae

K. L. Wyres, R. R. Wick, L. M. Judd, R. Froumine, A. Tokolyi, C. L. Gorrie, M. M. C. Lam, S. Duchene, A. Jenney, K. E. Holt

The paper compares the evolutionary dynamics of horizontal gene transfer in drug-resistant and virulent Klebsiella pneumoniae clones to assess the risk of gene convergence.

bioRxiv · Sep 12, 2018Microbiology

Genetic diversity, mobilisation and spread of the yersiniabactin-encoding mobile element ICEKp in Klebsiella pneumoniae populations

M. M. C. Lam, R. R. Wick, K. L. Wyres, C. Gorrie, L. M. Judd, A. Jenney, S. Brisse, K. E. Holt

The paper analyzes the prevalence and evolution of yersiniabactin-encoding mobile elements in Klebsiella pneumoniae using whole genome sequences, identifying diverse lineages and novel dispersal mechanisms.

bioRxiv · Mar 12, 2018Microbiology