Author

A. K. Wagner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Research Focus:development & morphogenesis· 1 Assay:flow cytometry· 1

Frequent Co-Authors

B. J. Chambers· 2 shared N. Kadri· 2 shared P. Riese· 2 shared A. Achour· 1 shared A. Barragan· 1 shared A. K. Bhandage· 1 shared B. Chambers· 1 shared C. Mayer· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

B. J. Chambers

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4 papers

Recent·Most cited

Jagged1 overexpression on T cells induces thymic regulatory T cells leading to thymic involution

J. Kritikou, I. Sanchez-Pascual, J. P. Munoz-Miranda, N. Vashist, A. K. Wagner, X. M. Zhang, E. Assarsson, M. Dominguez-Villar, H. Yagita, F. Garcia-Cozar, P. Riese, R. A. Harris, H.-G. Ljunggrean, B. Chambers

This study identifies Jagged1 overexpression in T cells as a driver of thymic involution through increased regulatory T cells, observed in a mouse model with thymic atrophy.

bioRxiv · Aug 25, 2022 · PreprintImmunology

Control of NK cell tolerance in MHC class I-deficiency by regulated SHP-1 localization to the activating immune synapse

L. Schmied, T. T. Luu, J. N. Sondergaard, S. Meinke, D. K. Mohammad, S. B. Singh, C. Mayer, G. Perinetti Casoni, M. Chrobok, H. Schlums, G. Rota, H. M. Truong, L. S. Westerberg, G. Guarda, E. Alici, , P. Hoglund

The paper shows that SHP-1 localization in NK cell synapses regulates tolerance in MHC class I-deficient cells through transcriptional and spatial mechanisms.

bioRxiv · Mar 8, 2022 · PreprintImmunology

PD-1 expression on NK cells can be related to cytokine stimulation and tissue residency

A. K. Wagner, N. Kadri, C. Tibbit, K. van de Ven, S. Bagawath-Singh, D. Oliinyk, E. LeGresly, N. Campbell, S. Trittel, P. Riese, T. Sandalova, A. Achour, K. Karre, B. J. Chambers

The paper investigates PD-1 expression on NK cells, showing its association with tumor-infiltrating NK cells and altered phenotypes in PD-1-deficient mice.

bioRxiv · Mar 29, 2021 · PreprintImmunology

GABAergic signaling in human and murine NK cells upon challenge with Toxoplasma gondii

A. K. Bhandage, L. M. Friedrich, S. Kanatani, S. Jakobsson-Bjoerken, J. I. Escrig-Larena, A. K. Wagner, B. J. Chambers, A. Barragan

NK cells synthesize and secrete GABA in response to T. gondii infection, which modulates their cytotoxicity and affects dendritic cell migration via GABA-A receptors.

bioRxiv · Mar 19, 2021Immunology