Author

G. Guarda

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Cavalli· 2 shared F. Bertoni· 2 shared P. Ventura· 2 shared A. J. Arribas· 1 shared A. K. Wagner· 1 shared A. Lupia· 1 shared A. M. Carrasco del Amor· 1 shared A. Rinaldi· 1 shared

Activity by Year

2022-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersImmunology

A. Cavalli

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Myc controls IL-15-driven expansion and translational machinery of NK cells

H. J. Khameneh, N. Fonta, A. Zenobi, C. Niogret, P. Ventura, C. Guerra, I. Kwee, A. Rinaldi, M. Pecoraro, R. Geiger, A. Cavalli, F. Bertoni, E. E. Vivier, A. Trumpp, G. Guarda

This study shows that Myc is essential for NK cell development, expansion, and anticancer immunity by regulating translational machinery and IL-15 responses.

bioRxiv · Dec 20, 2022 · PreprintImmunology

A first-in-class Wiskott-Aldrich syndrome protein (WASp) activator with anti-tumor activity in hematological cancers

F. Spriano, G. Sartori, L. Barnabei, A. J. Arribas, M. Guala, A. M. Carrasco del Amor, M. R. Tomasso, C. Tarantelli, L. Cascione, G. Golino, M. E. Riveiro, R. Bortolozzi, A. Lupia, F. Paduano, S. Huguet, , E. Gaudio

This paper develops EG-011, a first-in-class WASp activator with anti-tumor activity in hematological cancers, including resistant models.

bioRxiv · Nov 25, 2022 · PreprintCancer Biology

Control of NK cell tolerance in MHC class I-deficiency by regulated SHP-1 localization to the activating immune synapse

L. Schmied, T. T. Luu, J. N. Sondergaard, S. Meinke, D. K. Mohammad, S. B. Singh, C. Mayer, G. Perinetti Casoni, M. Chrobok, H. Schlums, G. Rota, H. M. Truong, L. S. Westerberg, G. Guarda, E. Alici, , P. Hoglund

The paper shows that SHP-1 localization in NK cell synapses regulates tolerance in MHC class I-deficient cells through transcriptional and spatial mechanisms.

bioRxiv · Mar 8, 2022 · PreprintImmunology