Author

S. B. Singh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. Subramanyam· 3 shared R. D. Mote· 2 shared A. K. Wagner· 1 shared A. Korkegian· 1 shared a. majumdar· 1 shared A. Nandi· 1 shared A. Sharma· 1 shared B. Sunde· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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3 shared papersCell Biology

D. Subramanyam

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Pathogenic aggregates alter actin organization and cellular viscosity resulting in stalled clathrin mediated endocytosis

S. B. Singh, S. S. Rajput, A. Sharma, V. Ananthanarayanan, A. Nandi, S. P. V. Patil, a. majumdar, D. Subramanyam

This study shows that pathogenic protein aggregates disrupt actin organization and cellular viscosity, impairing clathrin-mediated endocytosis in neurodegenerative conditions.

bioRxiv · Jul 10, 2023 · PreprintCell Biology

Control of NK cell tolerance in MHC class I-deficiency by regulated SHP-1 localization to the activating immune synapse

L. Schmied, T. T. Luu, J. N. Sondergaard, S. Meinke, D. K. Mohammad, S. B. Singh, C. Mayer, G. Perinetti Casoni, M. Chrobok, H. Schlums, G. Rota, H. M. Truong, L. S. Westerberg, G. Guarda, E. Alici, , P. Hoglund

The paper shows that SHP-1 localization in NK cell synapses regulates tolerance in MHC class I-deficient cells through transcriptional and spatial mechanisms.

bioRxiv · Mar 8, 2022 · PreprintImmunology

E-cadherin regulates the stability and transcriptional activity of β-catenin in embryonic stem cells

S. Bhattacharyya, R. D. Mote, J. Freimer, S. B. Singh, S. Arumugam, Y. V. Narayana, R. Rajan, D. Subramanyam

This study shows E-cadherin stabilizes and activates β-catenin in mouse ESCs, influencing cell-state-dependent gene expression and differentiation.

bioRxiv · Jul 22, 2021 · PreprintCell Biology

Loss of clathrin heavy chain enhances actin-dependent stiffness of mouse embryonic stem cells

R. D. Mote, J. Yadav, S. B. Singh, M. Tiwari, S. P. Patil, D. Subramanyam

This study shows that loss of clathrin heavy chain in mESCs increases cellular stiffness via actin stress fibers, without restoring pluripotency gene expression.

bioRxiv · May 10, 2020 · PreprintCell Biology

Identification of cyclic hexapeptides natural products with inhibitory potency against Mycobacterium tuberculosis

S. B. Singh, J. Odingo, M. A. Bailey, B. Sunde, A. Korkegian, T. O'Malley, Y. Ovechkina, T. R. Ioerger, J. C. Sacchettini, K. Young, D. B. Olsen, T. Parish

The paper screens 500 natural products for anti-tubercular activity, identifies five active cyclic hexapeptides, and shows structural analogs lack activity.

bioRxiv · Mar 10, 2018Microbiology