Author

A. Kelly

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Evolutionary Biology· 2 Cell Biology· 1 Ecology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Approach:statistical model· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2

Frequent Co-Authors

D. Hervieux· 2 shared M. Manseau· 2 shared P. Lavender· 2 shared A. A. Hoffmann· 1 shared A. Asimaki· 1 shared A. Draghi· 1 shared A. Freeman· 1 shared A. K. Wheatley· 1 shared

Activity by Year

2020-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersEcology

D. Hervieux

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Immune-profiling of T helper 1 (Th1), Th2 and Th17 signatures in murine splenocytes by targeting intracellular cytokines

S. Barman, A. Kelly, D. Dong, A. Patel, M. J. Buonopane, J. Gonzales, B. Janoschek, A. Draghi, D. J. Dowling

The paper develops a 17-parameter spectral flow cytometry panel to profile Th1, Th2, and Th17 cytokine signatures in murine splenocytes under steady-state and stimulated conditions.

Cytometry Part A · Mar 17, 2025Peer-reviewedImmunology

Genetic network analysis uncovers spatial variation in diversity and connectivity of a species presenting a continuous distribution

C. Fournier, M. Manseau, B. Redquest, L. Andrew, A. Kelly, D. Hervieux, T. Hegel, G. Pittoello, V. Trim, D. Brannen, P. Wilson

The paper develops a framework combining genetic network analysis and population genetics to assess connectivity and diversity in woodland caribou with continuous distributions, revealing isolation by distance and genetic erosion at range boundaries.

Global Ecology and Conservation · Oct 1, 2024Peer-reviewedEcology

Inhibition of Soluble Epoxide Hydrolase Reduces Inflammation and Myocardial Injury in Arrhythmogenic Cardiomyopathy

D. Panigrahy, A. Kelly, W. Wang, J. Yang, S. H. Hwang, M. Gillespie, I. Howard, C. Bueno-Beti, A. Asimaki, V. Penna, K. Lavine, M. Edin, D. Zeldin, B. Hammock, J. Saffitz

This study shows that inhibiting soluble epoxide hydrolase reduces inflammation and myocardial injury in arrhythmogenic cardiomyopathy by increasing pro-resolving lipid mediators.

bioRxiv · Feb 17, 2024Cell Biology

Monoclonal antibodies against human coronavirus NL63 spike

M. Conlan, H.-X. Tan, R. Esterbauer, A. Kelly, S. J. Kent, A. K. Wheatley, W. S. Lee

The paper characterises humoral responses and isolates neutralising antibodies against the NL63 coronavirus spike protein in healthy adults.

bioRxiv · Mar 12, 2023 · PreprintMicrobiology

Expanding risk predictions of pesticide resistance evolution in arthropod pests with a proxy for selection pressure

J. A. Thia, J. Maino, A. Kelly, A. A. Hoffmann, P. A. Umina

This paper uses pesticide product registrations as a proxy for selection pressure to predict resistance risk in agricultural arthropod pests, showing a positive association between pesticide use and resistance status.

bioRxiv · Apr 18, 2022Evolutionary Biology

Major diversification of caribou shaped by glacial cycles before the Last Glacial Maximum

R. S. Taylor, M. Manseau, C. F. C. Klutsch, J. L. Polfus, A. Steedman, D. Hervieux, A. Kelly, N. C. Larter, M. Gamberg, H. Schwantje, P. J. Wilson

This study shows that caribou diversification and introgression occurred before the Last Glacial Maximum, with major splits around 110 kya and large effective population sizes.

bioRxiv · Nov 30, 2020Evolutionary Biology

An autocrine Vitamin D-driven Th1 shutdown program can be exploited for COVID-19

R. McGregor, D. Chauss, T. Freiwald, B. Yan, L. Wang, E. Nova-Lamperti, Z. Zhang, H. Teague, E. West, J. Bibby, A. Kelly, A. Malik, A. Freeman, D. Schwartz, D. Portilla, , B. Afzali

This study identifies a Vitamin D-driven mechanism that suppresses excessive Th1 responses in COVID-19, suggesting potential therapeutic use of Vitamin D analogs.

bioRxiv · Jul 18, 2020 · PreprintImmunology

GATA3 controls mitochondrial biogenesis in primary human CD4+ T cells during DNA damage

L. A. Callender, J. Schroth, E. C. Carroll, L. E. L. Romano, E. Hendy, A. Kelly, P. Lavender, A. N. Akbar, J. P. Chapple, S. M. Henson

This study identifies a novel mechanism by which GATA3 regulates mitochondrial biogenesis in primary human CD4+ T cells in response to DNA damage.

bioRxiv · May 15, 2020 · PreprintImmunology