Author

A. L. Chang-Graham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

J. M. Hyser· 3 shared A. C. Strtak· 2 shared J. L. Perry· 2 shared M. K. Estes· 2 shared A. A. Philip· 1 shared C. Tomaro-Duchesneau· 1 shared H. A. Danhof· 1 shared J. M. Criglar· 1 shared

Activity by Year

2019-2019 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersMicrobiology

J. M. Hyser

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Author profile →

3 papers

Recent·Most cited

Recovirus NS1-2 has viroporin activity that induces aberrant cellular calcium signaling to facilitate virus replication

A. C. Strtak, J. L. Perry, M. N. Sharp, A. L. Chang-Graham, T. Farkas, J. M. Hyser

This study identifies the NS1-2 protein of Tulane virus as a viroporin that disrupts calcium homeostasis, facilitating virus replication by altering cellular calcium signaling.

bioRxiv · Jul 16, 2019Microbiology

Rotavirus Calcium Dysregulation Manifests as Dynamic Calcium Signaling in the Cytoplasm and Endoplasmic Reticulum

A. L. Chang-Graham, J. L. Perry, A. C. Strtak, N. K. Ramachandran, J. M. Criglar, A. A. Philip, J. T. Patton, M. K. Estes, J. M. Hyser

This study characterizes dynamic calcium signaling during rotavirus infection, showing increased cytosolic calcium spikes and ER release, with NSP4 and SOCE playing key roles.

bioRxiv · May 6, 2019Microbiology

Human intestinal enteroids with inducible neurogenin-3 expression as a novel model of gut hormone secretion

A. L. Chang-Graham, H. A. Danhof, M. A. Engevik, C. Tomaro-Duchesneau, U. C. Karandikar, M. K. Estes, J. Versalovic, R. A. Britton, J. M. Hyser

This paper develops a method to increase enteroendocrine cells in human intestinal enteroids using inducible neurogenin-3 expression, enabling functional studies of gut hormone secretion.

bioRxiv · Mar 16, 2019Microbiology