Author

A. L. Marsden

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 6 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:imaging· 5 Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Organism:mouse· 3 Research Focus:development & morphogenesis· 2 Approach:simulation· 2 Approach:statistical model· 2

Frequent Co-Authors

D. B. Ennis· 2 shared D. B. McElhinney· 2 shared J. M. Szafron· 2 shared M. Rabinovitch· 2 shared P. J. Nair· 2 shared W. Yang· 2 shared A. Cao· 1 shared A. Lai· 1 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersBioengineering

D. B. Ennis

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Assessing the Impact of Valve Sizing and Orientation on Bioprosthetic Pulmonary Valve Hemodynamics Using In Vitro 4D-Flow MRI

N. K. Schaivone, P. J. Nair, C. J. Elkins, D. B. McElhinney, D. B. Ennis, J. K. Eaton, A. L. Marsden

This study examines how bioprosthetic pulmonary valve sizing and orientation affect hemodynamics and performance using in vitro 4D-Flow MRI and imaging.

bioRxiv · May 9, 2024 · PreprintBioengineering

High Shear Stress Reduces ERG Causing Endothelial-Mesenchymal Transition and Pulmonary Arterial Hypertension

T. Shinohara, J.-R. A. J. Moonen, Y. H. Chun, Y. C. Lee-Yow, K. Okamura, J. M. Szafron, J. Kaplan, A. Cao, L. Wang, S. Taylor, S. Isobe, M. Dong, W. Yang, K. Guo, B. D. Franco, , M. Rabinovitch

The paper shows high shear stress induces endothelial-mesenchymal transition and pulmonary arterial hypertension by reducing ERG expression, which can be mitigated by ERG replenishment.

bioRxiv · Feb 2, 2024Cell Biology

Longitudinal Investigation of Aortic Dissection in Mice with Computational Fluid Dynamics

K. Baeumler, E. H. Phillips, N. G. Gutierrez, D. Fleischmann, A. L. Marsden, C. J. Goergen

This study uses computational fluid dynamics to analyze false lumen thrombus formation in mice with aortic dissection, finding that flow stagnation correlates with increased thrombus ratio and endothelial activation.

bioRxiv · Apr 24, 2023Bioengineering

A Computational Growth and Remodeling Framework for Adaptive and Maladaptive Pulmonary Arterial Hemodynamics

J. M. Szafron, W. Yang, J. A. Feinstein, M. Rabinovitch, A. L. Marsden

This paper develops a computational framework to simulate adaptive and maladaptive pulmonary arterial hemodynamics and identify contributors to PAH phenotypes.

bioRxiv · Apr 20, 2023Bioengineering

Hemodynamics in Patients with Aortic Coarctation: A Comparison of in vivo 4D-Flow MRI and FSI Simulation

P. J. Nair, M. R. Pfaller, S. A. Dual, M. Loecher, D. B. McElhinney, D. B. Ennis, A. L. Marsden

This study compares in vivo 4D-Flow MRI and FSI simulations in patients with aortic coarctation to assess their agreement in quantifying hemodynamics.

bioRxiv · Feb 13, 2023 · PreprintBioengineering

Blood flow modeling reveals improved collateral artery performance during mammalian heart regeneration

S. Anbazhakan, P. E. Rios Coronado, A. N. L. Sy-Quia, A. Seow, A. M. Hands, C. K. Cook, M. Zhao, M. L. Dong, M. Pfaller, D. Bernstein, B. C. Raftrey, K. Nieman, A. M. Pasca, A. L. Marsden, K. Red-Horse

This study uses computational modeling to show neonatal collateral arteries are more effective than adult ones in restoring blood flow during heart regeneration.

bioRxiv · Sep 17, 2021 · PreprintBioengineering

Computational Simulations of the 4-D Micro-Circulatory Network in Zebrafish Tail Amputation and Regeneration

M. Roustaei, K. I. Baek, Z. Wang, S. Cavallero, S. Satta, A. Lai, R. O'Donnell, V. Vedula, Y. Ding, A. L. Marsden, T. Hsiai

This study uses computational fluid dynamics to model microvascular changes in zebrafish tail regeneration, showing dynamic shifts in wall shear stress and flow rate during vascular remodeling.

bioRxiv · Feb 10, 2021 · PreprintBioengineering