Author

T. Shinohara

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Evolutionary Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 4 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2

Frequent Co-Authors

A. Cao· 2 shared J. Kaplan· 2 shared L. Wang· 2 shared M. Rabinovitch· 2 shared S. Isobe· 2 shared S. Taylor· 2 shared A. Hsi· 1 shared A. J. Sweatt· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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2 shared papersCell Biology

A. Cao

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

High Shear Stress Reduces ERG Causing Endothelial-Mesenchymal Transition and Pulmonary Arterial Hypertension

T. Shinohara, J.-R. A. J. Moonen, Y. H. Chun, Y. C. Lee-Yow, K. Okamura, J. M. Szafron, J. Kaplan, A. Cao, L. Wang, S. Taylor, S. Isobe, M. Dong, W. Yang, K. Guo, B. D. Franco, , M. Rabinovitch

The paper shows high shear stress induces endothelial-mesenchymal transition and pulmonary arterial hypertension by reducing ERG expression, which can be mitigated by ERG replenishment.

bioRxiv · Feb 2, 2024Cell Biology

Hypoxic conditions promote Candida glabrata colonization in the intestinal tract and EPA6 plays a significant role in hypoxic adhesion to intestinal cells

T. Shinohara, M. Abe, S. Sadamoto, M. Nagi, H. Katano, H. Chibana, Y. Miyazaki

This study shows hypoxia enhances Candida glabrata adhesion to intestinal cells, with EPA6 playing a key role in this process.

bioRxiv · Jul 1, 2022 · PreprintMicrobiology

Experimental evolution of extremophile levels of radiation resistance in Escherichia coli

S. T. Bruckbauer, B. B. Minkoff, T. Shinohara, A. Lipzen, J. Guo, E. A. Wood, M. R. Sussman, C. Pennacchio, M. M. Cox

This study uses experimental evolution to generate E. coli with radiation resistance similar to Deinococcus radiodurans, revealing multiple genomic and proteomic changes involved in IR resistance.

bioRxiv · Oct 18, 2021 · PreprintEvolutionary Biology

Endogenous Retroviral Elements Generate Pathologic Neutrophils and Elastase Rich Exosomes in Pulmonary Arterial Hypertension

S. Taylor, K. Contrepois, B. Benayoun, L. A. Jiang, S. Isobe, L. Wang, S. Melemenidis, M. O. Ozen, S. Otsuki, T. Shinohara, A. J. Sweatt, J. Kaplan, A. Cao, J.-R. Moonen, D. P. Marciano, , M. Rabinovitch

The paper shows that endogenous retroviruses contribute to neutrophil dysfunction and exosome-mediated pulmonary arterial hypertension.

bioRxiv · Jan 8, 2021Immunology