J. Kaplan

Movement execution defines a distinct neural state in dyskinesia and enhances decoding

The paper identifies movement execution as a distinct neural state in Parkinson's dyskinesia, showing it enhances decoding of dyskinesia through specific oscillatory patterns.

High Shear Stress Reduces ERG Causing Endothelial-Mesenchymal Transition and Pulmonary Arterial Hypertension

The paper shows high shear stress induces endothelial-mesenchymal transition and pulmonary arterial hypertension by reducing ERG expression, which can be mitigated by ERG replenishment.

Mon1a and FCHO2 are required for maintenance of Golgi architecture

This study shows that Mon1a and FCHO2 are required for maintaining Golgi architecture, with Mon1a interacting with dynein and FCHO2 forming lateral links between Golgi ministacks.

Zn2+ potentiation of OTOP proton channels identifies structural elements of the gating apparatus

This paper identifies structural elements in the OTOP channel family that mediate Zn2+ activation, revealing the tm 11-12 linker as part of the gating apparatus.

Structural motifs for subtype-specific pH-sensitive gating of vertebrate otopetrin proton channels

This study identifies structural motifs in OTOP channels that determine subtype-specific pH sensitivity, showing that proton gating is mediated by extracellular linkers in the N and C domains.

Endogenous Retroviral Elements Generate Pathologic Neutrophils and Elastase Rich Exosomes in Pulmonary Arterial Hypertension

The paper shows that endogenous retroviruses contribute to neutrophil dysfunction and exosome-mediated pulmonary arterial hypertension.

Breast cancer endocrine therapy exhausts adipocyte progenitors promoting weight gain and glucose intolerance

This study shows that breast cancer endocrine therapies deplete adipocyte progenitors and promote weight gain and glucose intolerance, especially in obese mice.