Author

J. M. Szafron

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. L. Marsden· 2 shared M. Rabinovitch· 2 shared W. Yang· 2 shared A. B. Ramachandra· 1 shared A. Cao· 1 shared A. Giudici· 1 shared B. D. Franco· 1 shared B. Spronck· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

A. L. Marsden

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Author profile →

3 papers

Recent·Most cited

High Shear Stress Reduces ERG Causing Endothelial-Mesenchymal Transition and Pulmonary Arterial Hypertension

T. Shinohara, J.-R. A. J. Moonen, Y. H. Chun, Y. C. Lee-Yow, K. Okamura, J. M. Szafron, J. Kaplan, A. Cao, L. Wang, S. Taylor, S. Isobe, M. Dong, W. Yang, K. Guo, B. D. Franco, , M. Rabinovitch

The paper shows high shear stress induces endothelial-mesenchymal transition and pulmonary arterial hypertension by reducing ERG expression, which can be mitigated by ERG replenishment.

bioRxiv · Feb 2, 2024Cell Biology

Instability in computational models of vascular smooth muscle cell contraction

A. Giudici, J. M. Szafron, A. B. Ramachandra, B. Spronck

This paper identifies unstable behaviors in active stress models of vascular smooth muscle cell contraction using limited and extensive experimental data.

bioRxiv · Oct 16, 2023Biophysics

A Computational Growth and Remodeling Framework for Adaptive and Maladaptive Pulmonary Arterial Hemodynamics

J. M. Szafron, W. Yang, J. A. Feinstein, M. Rabinovitch, A. L. Marsden

This paper develops a computational framework to simulate adaptive and maladaptive pulmonary arterial hemodynamics and identify contributors to PAH phenotypes.

bioRxiv · Apr 20, 2023Bioengineering