Nanomechanical phenotyping uncovers a non-canonical smooth muscle-like hypercontractility program in lung squamous cell carcinoma myofibroblasts
A. Calo, A. Bernardo, N. D. Valdivia, A. Labernadie, V. Batto, J. Rodriguez-Rojas, M. Vizoso, B. Cantero, M. Arshakyan, M. R. Pasto, L. Huetter, A. Parker, M. Kumar, N. Gavara, G. Gomila, , Jordi Alcaraz
The paper identifies a non-canonical smooth muscle-like hypercontractility program in LUSC myCAFs using nanomechanical phenotyping, linking it to tumor mechanics and adverse outcomes.
bioRxiv · Nov 9, 2026 · PreprintBiophysics