Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
L. Rossetti, S. Grosser, J. F. Abenza, L. Valon, P. Roca-Cusachs, R. Alert, X. Trepat
The paper uses optogenetic Rac1 activation to generate leader cells and shows that collective cell migration requires global mechanical organization rather than autonomous leader action.
Nature Physics · Aug 12, 2024Peer-reviewedCell Biology
S. Conti, V. Venturini, A. Canellas-Socias, C. Cortina, J. F. Abenza, C. S.-O. Attolini, E. M. Guerra, C. K. Xu, J. H. Li, L. Rossetti, G. Stassi, P. Roca-Cusachs, A. Diz-Munoz, V. Ruprecht, J. Guck, , X. Trepat
This study identifies mechanical phenotype differences between LGR5+ and LGR5- colorectal cancer cells, linking them to membrane to cortex attachment proteins and metastatic potential.
bioRxiv · Dec 4, 2023Cancer Biology
E. Vercruysse, D. B. Brückner, M. Gomez-Gonzalez, M. Luciano, Y. Kalukula, L. Rossetti, X. Trepat, E. Hannezo, S. GABRIELE
This study investigates how the geometry of microstripes affects the migration efficiency of epithelial cell clusters and identifies interaction rules governing their movement in complex environments.
bioRxiv · Jul 17, 2022Biophysics
J. F. Abenza, L. Rossetti, M. Mouelhi, J. Burgues, I. Andreu, K. Kennedy, P. Roca-Cusachs, S. Marco, J. Garcia-Ojalvo, X. Trepat
The paper shows mechanical cues regulate the circadian clock in fibroblasts via YAP/TAZ and TEAD, disrupting Rev-erb oscillations when YAP/TAZ translocate to the nucleus.
bioRxiv · Feb 4, 2022Cell Biology
N. Hino, L. Rossetti, A. Marin-Llaurado, K. Aoki, X. Trepat, M. Matsuda, T. Hirashima
This study shows that ERK-mediated mechanochemical waves coordinate intercellular signaling to direct collective cell migration through long-range polarity alignment.
bioRxiv · Dec 25, 2019Cell Biology