Author

A. Laumaea

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 7 Immunology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 8 Research Focus:host-pathogen & immune response· 8 Organism:human· 8 Assay:proteomics· 7 Research Focus:cell type annotation· 4 Research Focus:differential expression· 3 Research Focus:clustering· 2 Assay:flow cytometry· 2

Frequent Co-Authors

A. Finzi· 10 shared G. Beaudoin-Bussieres· 9 shared H. Medjahed· 8 shared R. Gasser· 8 shared J. Richard· 7 shared G. Gendron-Lepage· 6 shared J. Prevost· 6 shared R. Bazin· 6 shared

Activity by Year

2020-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

10 shared papersMicrobiology

A. Finzi

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

Small CD4 mimetics sensitize HIV-1-infected macrophages to antibody-dependent cellular cytotoxicity

A. Laumaea, L. Marchitto, G. Beaudoin-Bussieres, S. Ding, R. Gasser, D. Chatterjee, G. Gendron-Lepage, H. Medjahed, H.-C. Chen, A. B. Smith, H. Ding, J. C. Kappes, B. H. Hahn, F. Kirchhoff, J. Richard, , A. Finzi

The paper shows that small CD4 mimetics expose ADCC epitopes on HIV-1-infected macrophages, making them susceptible to antibody-dependent cellular cytotoxicity.

bioRxiv · Jun 30, 2022Microbiology

The Fc-effector function of COVID-19 convalescent plasma contributes to SARS-CoV-2 treatment efficacy in mice

I. Ullah, G. Beaudoin-Bussieres, K. Symmes, M. Cloutier, E. Ducas, A. Tauzin, A. Laumaea, P. Begin, W. Mothes, R. Bazin, A. Finzi, P. D. Uchil

This study shows that CCPs with high Fc-effector activity, rather than just neutralizing ability, are more effective in treating SARS-CoV-2 in mice.

bioRxiv · Jun 10, 2022Immunology

SARS-CoV-2 Omicron Spike recognition by plasma from individuals receiving BNT162b2 mRNA vaccination with a 16-weeks interval between doses

D. Chatterjee, A. Tauzin, L. Marchitto, S. Y. Gong, M. Boutin, C. Bourassa, G. Beaudoin-Bussieres, Y. Bo, S. Ding, A. Laumaea, D. Vezina, J. Perreault, L. Gokool, C. Morrisseau, P. Arlotto, , A. Finzi

This study evaluates how plasma from individuals with a 16-week interval between BNT162b2 mRNA vaccine doses recognizes and neutralizes the Omicron Spike compared to other variants.

bioRxiv · Dec 21, 2021Microbiology

Temporal associations of B and T cell immunity with robust vaccine responsiveness in a 16-week interval BNT162b2 regimen

M. Nayrac, M. Dube, G. Sannier, A. Nicolas, L. Marchitto, O. Tastet, A. Tauzin, N. Brassard, G. Beaudoin-Bussieres, D. Vezina, S. Y. Gong, M. Benlarbi, R. Gasser, A. Laumaea, C. Bourassa, , D. E. Kaufmann

The paper examines B and T cell immunity responses to a 16-week interval BNT162b2 vaccine regimen, finding robust immune memory and functional associations between immune components.

bioRxiv · Dec 18, 2021Immunology

A single BNT162b2 mRNA dose elicits antibodies with Fc-mediated effector functions and boost pre-existing humoral and T cell responses

A. Tauzin, M. Nayrac, M. Benlarbi, S. Y. Gong, R. Gasser, G. Beaudoin-Bussieres, N. Brassard, A. Laumaea, D. Vezina, J. Prevost, S. P. Anand, C. Bourassa, G. Gendron-Lepage, H. Medjahed, G. Goyette, , A. Finzi

This study shows a single dose of the BNT162b2 mRNA vaccine elicits strong antibody and T cell responses, including Fc-mediated effector functions, and boosts pre-existing immunity in previously infected individuals.

bioRxiv · Mar 18, 2021 · PreprintImmunology

Longitudinal analysis of humoral immunity against SARS-CoV-2 Spike in convalescent individuals up to 8 months post-symptom onset

S. P. Anand, J. Prevost, M. Nayrac, G. Beaudoin-Bussieres, M. Benlarbi, R. Gasser, N. Brassard, A. Laumaea, S. Y. Gong, C. Bourassa, E. Brunet-Ratnasingham, H. Medjahed, G. Gendron-Lepage, G. Goyette, L. Gokool, , A. Finzi

This study tracks humoral immune responses in convalescent individuals up to 8 months post-SARS-CoV-2 infection, showing that IgG+ memory B cells persist while plasma antibody levels decline.

bioRxiv · Jan 25, 2021Microbiology

Major role of IgM in the neutralizing activity of convalescent plasma against SARS-CoV-2

R. Gasser, M. Cloutier, J. Prevost, C. Fink, E. Ducas, S. Ding, N. Dussault, P. Landry, T. Tremblay, A. Laforce-Lavoie, A. Lewin, G. Beaudoin-Bussieres, A. Laumaea, H. Medjahed, C. Larochelle, , A. Finzi

This study shows that IgM plays a major role in neutralizing SARS-CoV-2 in convalescent plasma, with its depletion causing the greatest loss of neutralizing activity.

bioRxiv · Oct 9, 2020Microbiology

Real-time conformational dynamics of SARS-CoV-2 spikes on virus particles

M. Lu, P. D. Uchil, W. Li, D. Zheng, D. S. Terry, J. Gorman, W. Shi, B. Zhang, T. Zhou, S. Ding, R. Gasser, J. Prevost, G. Beaudoin-Bussieres, S. P. Anand, A. Laumaea, , W. Mothes

This study uses smFRET to observe real-time conformational dynamics of SARS-CoV-2 spikes on virus particles, revealing multiple states and mechanisms of neutralization by antibodies and convalescent plasma.

bioRxiv · Sep 10, 2020Microbiology

Antibody binding to SARS-CoV-2 S glycoprotein correlates with, but does not predict neutralization

S. Ding, A. Laumaea, R. Gasser, H. Medjahed, M. Pancera, L. Stamatatos, A. McGuire, R. Bazin, A. Finzi

bioRxiv · Sep 8, 2020Microbiology

Cross-sectional evaluation of humoral responses against SARS-CoV-2 Spike

J. Prevost, R. Gasser, G. Beaudoin-Bussieres, J. Richard, R. Duerr, A. Laumaea, S. P. Anand, G. Goyette, M. Benlarbi, S. Ding, H. Medjahed, A. Lewin, J. Perreault, T. Tremblay, G. Gendron-Lepage, , A. Finzi

This study evaluates humoral responses against SARS-CoV-2 Spike in 106 infected individuals, finding persistent RBD-specific IgG and declining neutralizing activity over time.

bioRxiv · Jun 8, 2020Microbiology