Author

A. McGuire

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 6 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Research Focus:host-pathogen & immune response· 6 Organism:mouse· 4 Assay:proteomics· 4 Organism:human· 3 Assay:imaging· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

L. Stamatatos· 5 shared M. Pancera· 4 shared A. Finzi· 3 shared H. Medjahed· 2 shared L. Homad· 2 shared N. Hurlburt· 2 shared R. Gasser· 2 shared S. Ding· 2 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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5 shared papersImmunology

L. Stamatatos

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Antigen-level resolution of commensal-specific B cell responses enabled by phage-display screening and B cell tetramers

S. Verma, M. J. Dufort, T. M. Olsen, J. C. Labuda, S. Kimmel, S. Scharffenberger, A. McGuire, O. J. Harrison

This study identifies SFB-specific B cell responses using phage display and tetramers, revealing compartmentalized activation and isotype gradients in the gut.

bioRxiv · Oct 13, 2023Immunology

Immunization with a self-assembling nanoparticle vaccine displaying EBV gH/gL protects humanized mice against lethal viral challenge

H. Malhi, L. J. Homad, Y.-H. Wan, B. Poudel, B. Fiala, A. J. Borst, J. Y. Wang, C. Walkey, J. Price, A. Wall, S. Singh, Z. Moodie, S. Handa, C. Correnti, B. L. Stoddard, , A. McGuire

This study evaluates a nanoparticle vaccine displaying EBV gH/gL, showing it protects humanized mice against lethal EBV challenge, while monomeric gH/gL does not.

bioRxiv · Feb 17, 2022Immunology

Structural definition of a pan-sarbecovirus neutralizing epitope on the spike S2 subunit.

N. Hurlburt, L. Homad, I. Siha, M. F. Jenewein, A. MacCamy, Y.-H. Wan, J. Boonyaratanakornkit, A. M. Sholukh, P. Zhou, D. Burton, R. Andrabi, L. Stamatatos, M. Pancera, A. McGuire

This paper identifies a conserved neutralizing epitope on the spike S2 subunit of sarbecoviruses, demonstrating cross-neutralization against multiple variants and a bat coronavirus.

bioRxiv · Aug 2, 2021Immunology

Isolation and Characterization of Cross-Neutralizing Coronavirus Antibodies from COVID-19+ Subjects

M. Jennewein, A. MacCamey, N. Akins, J. Feng, L. Homad, N. Hurlburt, E. Seydoux, Y.-H. Wang, A. B. Stuart, V. V. Edara, K. Floyd, A. Vanderheiden, J. R. Mascola, N. Doria-Rose, L. Wang, , L. Stamatatos

The paper isolates and characterizes cross-neutralizing antibodies from COVID-19 patients, identifying antibodies that neutralize both SARS-CoV-1 and SARS-CoV-2, including variants.

bioRxiv · Mar 23, 2021 · PreprintImmunology

Live imaging of SARS-CoV-2 infection in mice reveals neutralizing antibodies require Fc function for optimal efficacy

I. Ullah, J. Prevost, M. S. Ladinsky, H. Stone, M. Lu, S. P. Anand, G. Beaudoin-Bussieres, K. Symmes, M. Benlarbi, S. Ding, R. Gasser, C. Fink, Y. Chen, A. Tauzin, G. Goyette, , P. D. Uchil

This study uses live imaging to show that neutralizing antibodies against SARS-CoV-2 need both Fab and Fc functions to effectively prevent and resolve infection in mice.

bioRxiv · Mar 22, 2021Immunology

Antibody binding to SARS-CoV-2 S glycoprotein correlates with, but does not predict neutralization

S. Ding, A. Laumaea, R. Gasser, H. Medjahed, M. Pancera, L. Stamatatos, A. McGuire, R. Bazin, A. Finzi

bioRxiv · Sep 8, 2020Microbiology

Magnetic manipulation of axonal endosome transport in live neurons

P. C. Chowdary, A. McGuire, Y. Lee, D. Che, L. Hanson, Y. Osakada, C. Ooi, C. Xie, S. X. Wang, B. Cui

This paper introduces a method to control axonal endosome transport in live neurons using magnetic forces, revealing insights into dynein function and endosome dynamics.

bioRxiv · Aug 15, 2019 · PreprintBiophysics

Anti-HIV-1 B cell responses are dependent on B cell precursor frequency and antigen binding affinity

P. Dosenovic, E. E. Kara, A.-K. Pettersson, A. McGuire, M. Gray, H. Hartweger, E. S. Thientosapol, L. Stamatatos, M. C. Nussenzweig

This study investigates how B cell precursor frequency and antigen binding affinity influence germinal center recruitment and clonal expansion in HIV-1 vaccine development using adoptive transfer experiments.

bioRxiv · Mar 2, 2018Immunology