Author

A. Lladser

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Organism:human· 1

Frequent Co-Authors

D. Figueroa· 2 shared F. Osorio· 2 shared A. Hernandez-Oliveras· 1 shared C. De Nolf· 1 shared C. Fuentes· 1 shared C. Moreno· 1 shared D. Fernandez· 1 shared F. Ardiles· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

D. Figueroa

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Long-term efficacy of adoptive cell therapy is determined by host CD8+ T cells and undermined by lymphodepleting preconditioning

D. Figueroa, J. P. Vega, A. Hernandez-Oliveras, F. Galvez-Cancino, F. Ardiles, F. Flores, S. Hidalgo, X. Lopez, H. Gonzalez, F. Osorio, V. Borgna, A. Lladser

This study shows that host CD8+ T cells enhance adoptive cell therapy (ACT) efficacy against melanoma, while lymphodepleting preconditioning reduces long-term effectiveness by impairing host immunity.

bioRxiv · May 16, 2024 · PreprintImmunology

Nuanced role for dendritic cell intrinsic IRE1 RNase in the regulation of antitumor adaptive immunity.

F. Flores-Santibanez, S. Rennen, D. Fernandez, C. De Nolf, S. Gaete, C. Fuentes, C. Moreno, D. Figueroa, A. Lladser, T. Iwawaki, M. R. Bono, S. Janssens, F. Osorio

This study shows that IRE1 RNase activity in tumor-associated dendritic cells regulates antitumor immunity, with XBP1s deficiency leading to increased tumor growth and impaired T cell responses.

bioRxiv · Jul 20, 2022 · PreprintImmunology