A. M. Arvin

Caught in the Act: targeted mutagenesis of the herpesvirus fusogen central helix captures transition states

This study mutates the herpesvirus fusogen gB to capture its transition state, revealing the critical role of domain III in membrane fusion.

The N-terminus of varicella-zoster virus glycoprotein B has a functional role in fusion.

This study identifies the N-terminus of VZV glycoprotein B as critical for membrane fusion, showing that mutations in this region impair viral propagation.