Selective pharmaceutical inhibition of PARP14 mitigates allergen-induced IgE and mucus overproduction in a mouse model of pulmonary allergic response
A. M. Eddie, L. B. Schenkel, K. K. Swinger, J. R. Molina, K. Kunii, A. L. Raybuck, H. Keilhack, M. Niepel, R. S. Peebles, M. R. Boothby, S. H. Cho
This study shows that inhibiting PARP14's catalytic activity reduces allergen-induced IgE and mucus overproduction in a mouse model of allergic response.
ImmunoHorizons · Jul 1, 2022Peer-reviewedImmunology