Plasma cell differentiation, antibody quality, and initial germinal center B cell population depend on glucose influx rate
S. K. Brookens, S. H. Cho, Y. Paik, K. Meyer, A. L. Raybuck, C. Park, D. L. Greenwood, J. C. Rathmell, M. R. Boothby
This study shows that glucose influx is critical for germinal center function and plasma cell production, but plasma cells can also use alternative hexose sugars for antibody secretion.
bioRxiv · Sep 13, 2023Immunology