Author

A. M. House

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Organism:human· 2

Frequent Co-Authors

A. N. Littlejohn· 1 shared A. Walens· 1 shared B. L. Mouery· 1 shared B. Ma· 1 shared D. Dominguez· 1 shared D. Fleifel· 1 shared G. D. Grant· 1 shared H. Wu· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

A. N. Littlejohn

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2 papers

Recent·Most cited

Quantitative Profiling of Adaptation to Cyclin E Overproduction

J. C. Limas, A. N. Littlejohn, A. M. House, K. M. Kedziora, B. L. Mouery, B. Ma, D. Fleifel, A. Walens, M. M. Aleman, D. Dominguez, J. G. Cook

This study examines how mammalian cells adapt to chronic cyclin E overproduction, revealing that adaptation involves downregulation of G1-regulated genes and partial resistance to replication stress.

bioRxiv · Jul 26, 2021Cell Biology

Intrinsic checkpoint deficiency during cell cycle re-entry from quiescence

J. P. Matson, A. M. House, G. D. Grant, H. Wu, J. Perez, J. Cook

The paper shows that human cells re-entering the cell cycle from quiescence have impaired p53-dependent origin licensing and slow MCM loading, leading to underlicensed first S phases and increased replication stress sensitivity.

bioRxiv · Feb 22, 2019Cell Biology