Author

A. M. N. Walker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. Skromna· 2 shared M. Drozd· 2 shared N. J. Haywood· 2 shared N. Makava· 2 shared N. Warmke· 2 shared A. Moron· 1 shared A. Vidal-Puig· 1 shared C. Luk· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

A. Skromna

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2 papers

Recent·Most cited

Paracrine role for endothelial IGF-1 receptor in white adipocyte beiging

N. J. Haywood, K. Bridge, C. Luk, N. Warmke, K. Simmons, M. Drozd, A. Moron, S. Straw, J. Scragg, J. Smith, S. Limumpornpetch, C. Ozber, C. Wilkinson, A. Skromna, N. Makava, , M. Kearney

This study shows that reducing endothelial IGF-1R in nutrient excess promotes white adipocyte beiging, increases energy expenditure, and improves insulin sensitivity through paracrine malonic acid release.

bioRxiv · Dec 1, 2021 · PreprintCell Biology

Reduced insulin and IGF-1 signalling synergistically extend healthspan in male mice

A. M. N. Walker, N. T. Watt, N. Warmke, N. Y. Yuldasheva, M. Drozd, N. J. Haywood, A. Skromna, N. Makava, S. B. Wheatcroft, M. T. Kearney, R. M. Cubbon

This study shows that reducing both insulin and IGF-1 signaling in male mice synergistically extends healthspan, as evidenced by longer survival and preserved nesting behavior compared to single-gene knockouts.

bioRxiv · Mar 15, 2019 · PreprintCell Biology