Author

A. Manousopoulou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

S. D. Garbis· 2 shared A. A. Ritchie· 1 shared A. Cowie· 1 shared A. Hayden· 1 shared A. M. Grabowska· 1 shared B. Ashley· 1 shared B. P. Sharpe· 1 shared C. Cooper· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPhysiology

S. D. Garbis

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Author profile →

3 papers

Recent·Most cited

Placental uptake and metabolism of 25(OH)Vitamin D determines its activity within the fetoplacental unit

B. Ashley, C. Simner, A. Manousopoulou, C. Jenkinson, F. Hey, J. M. Frost, F. I. Rezwan, C. H. White, E. M. Lofthouse, E. Hyde, L. Cooke, S. Barton, P. Mahon, E. M. Curtis, R. J. Moon, , J. K. Cleal

This study shows the human placenta actively transports and metabolizes 25(OH)D3 into active vitamin D metabolites, influencing fetal development through placental transcriptome and proteome changes.

eLife · Mar 8, 2022Peer-reviewedPhysiology

Deep Proteome Profiling of Human Mammary Epithelia at Lineage and Age Resolution

S. Hinz, A. Manousopoulou, M. Miyano, R. W. Sayaman, K. Y. Aguilera, M. E. Todhunter, J. C. Lopez, L. L. Sohn, L. D. Wang, M. A. LaBarge

The paper profiles the proteome of human mammary epithelia across age and lineage, identifying age-related protein changes and potential therapeutic targets for breast cancer.

bioRxiv · Feb 2, 2021Cell Biology

Modulation of the tumour promoting functions of cancer associated fibroblasts by phosphodiesterase type 5 inhibition increases the efficacy of chemotherapy in human preclinical models of esophageal adenocarcinoma.

A. Hayden, A. Manousopoulou, A. Cowie, R. Walker, B. P. Sharpe, J. Harrington, F. Izadi, E. Kyle, J. H. Saunders, S. L. Parsons, A. A. Ritchie, P. A. Clarke, P. Collier, S. D. Garbis, M. Rose-Zerilli, , T. J. Underwood

This study shows that PDE5 inhibition reduces CAF tumor-promoting effects and enhances chemotherapy efficacy in EAC models.

bioRxiv · Apr 21, 2020 · PreprintCancer Biology