Author

A. Milewska

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 5 Organism:human· 4 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:proteomics· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

K. Pyrc· 6 shared A. Dabrowska· 3 shared M. Ochman· 3 shared A. Szczepanski· 2 shared K. Owczarek· 2 shared M. Urlik· 2 shared W. Branicki· 2 shared A. Arenas-Pinto· 1 shared

Activity by Year

2020-2020 · peak 6/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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6 shared papersMicrobiology

K. Pyrc

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

SARS-CoV-2 inhibition in human airway epithelial cells using a mucoadhesive, amphiphilic chitosan that may serve as an anti-viral nasal spray

K. Pyrc, A. Milewska, E. B. Duran, P. Botwina, R. Lopes, A. Arenas-Pinto, M. Badr, R. Mellor, T. Kalber, D. Fernandez-Reyes, A. G. Schatzlein, I. F. Uchegbu

This paper demonstrates that GCPQ, a mucoadhesive chitosan derivative, reduces SARS-CoV-2 infectivity in cell cultures and shows promising nasal retention in mice, supporting its potential as a nasal spray for COVID-19 prevention.

bioRxiv · Dec 10, 2020 · PreprintPharmacology & Toxicology

Zika virus NS3 protease and its cellular substrates

A. Dabrowska, A. Milewska, J. Ner-Kluza, P. Suder, K. Pyrc

This study investigates the cellular substrates of Zika virus NS3 protease but finds that biological validation is needed to confirm its protease activity's relevance.

bioRxiv · Sep 18, 2020 · PreprintMicrobiology

The SARS-CoV-2 ORF10 is not essential in vitro or in vivo in humans.

K. Pancer, A. Milewska, K. Owczarek, A. Dabrowska, W. Branicki, M. Sanak, K. Pyrc

The paper shows that SARS-CoV-2 ORF10 is not essential for viral replication or disease in humans, based on clinical and in vitro evidence.

bioRxiv · Aug 29, 2020Microbiology

HTCC as a highly effective polymeric inhibitor of SARS-CoV-2 and MERS-CoV

A. Milewska, Y. Chi, A. Szczepanski, E. Barreto-Duran, K. Liu, D. Liu, X. Guo, Y. Ge, J. Li, L. Cui, M. Ochman, M. Urlik, S. Rodziewicz-Motowidlo, F. Zhu, K. Szczubialka, , K. Pyrc

This paper evaluates HTCC as a potential inhibitor for SARS-CoV-2 and MERS-CoV, highlighting its antiviral activity against highly pathogenic coronaviruses.

bioRxiv · Mar 29, 2020 · PreprintMicrobiology

Replication of SARS-CoV-2 in human respiratory epithelium

A. Milewska, A. Kula-Pacurar, J. Wadas, A. Suder, A. Szczepanski, A. Dabrowska, K. Owczarek, M. Ochman, T. Stacel, Z. Rajfur, P. P. Labaj, W. Branicki, K. Pyrc

The paper presents a human airway epithelium model for studying SARS-CoV-2 replication and drug assessment, highlighting its potential as an alternative to animal models and Vero E6 cells.

bioRxiv · Mar 20, 2020Microbiology

Kallikrein 13: a new player in coronaviral infections.

A. Milewska, K. Falkowski, M. Kalinska, E. Bielecka, A. Naskalska, P. Mak, A. Lesner, M. Ochman, M. Urlik, J. Potempa, T. Kantyka, K. Pyrc

This study identifies KLK13 as a protease required for HCoV-HKU1 infection and shows it cleaves the viral S protein, determining tissue specificity and potential interspecies transmission.

bioRxiv · Mar 1, 2020 · PreprintMicrobiology