A. Nakanishi

Production of Infectious Reporter Murine Norovirus by VP2 trans-Complementation

This study shows that infectious murine norovirus can be produced by supplying exogenous VP2 when ORF3 is replaced with foreign genes.

Neonatal Fc receptor is a functional receptor for human astrovirus

This study identifies the neonatal Fc receptor as a functional receptor for human astrovirus using CRISPR screening and shows its role in viral entry.

Structural transition of the ground-state structure to steady-state structures by sequential binding of ATP to V/A-ATPase

The paper identifies intermediate structures of V/A-ATPase during ATP activation using cryo-EM, showing how the ground-state structure transitions to steady-state through sequential ATP binding.

Structural snapshots of V/A-ATPase reveal a new paradigm for rotary catalysis

The paper determines atomic models of V/A-ATPase catalytic intermediates, revealing a ratchet-like mechanism for unidirectional rotation instead of a power stroke model.

The mechanical inhibition of the isolated Vo from V-ATPase for proton conductance

The paper determines the cryo-EM structures of holo V/A-ATPase and isolated Vo to elucidate the auto-inhibited form of Vo and its regulation of proton conductance.