K. Yokoyama

How to control unpredictable others in court-net sports

The paper examines strategies in court net sports to control unpredictable behavior, finding skilled players use regularity to disrupt expectations and promote cooperation.

Mechanism of ATP hydrolysis dependent rotation of ATP synthases

The paper uses cryo-EM to capture catalytic intermediates of ATP synthase F1 domain, revealing how ATP hydrolysis couples to mechanical rotation in 120-degree steps.

Structural transition of the ground-state structure to steady-state structures by sequential binding of ATP to V/A-ATPase

The paper identifies intermediate structures of V/A-ATPase during ATP activation using cryo-EM, showing how the ground-state structure transitions to steady-state through sequential ATP binding.

A rapid and universal liquid chromatograph-mass spectrometry-based platform, refmAb-Q nSMOL, for monitoring monoclonal antibody therapeutics

This paper introduces a rapid and universal LC-MS-based platform for quantifying monoclonal antibodies, offering a scalable alternative to traditional ligand binding assays.

Structural snapshots of V/A-ATPase reveal a new paradigm for rotary catalysis

The paper determines atomic models of V/A-ATPase catalytic intermediates, revealing a ratchet-like mechanism for unidirectional rotation instead of a power stroke model.

The mechanical inhibition of the isolated Vo from V-ATPase for proton conductance

The paper determines the cryo-EM structures of holo V/A-ATPase and isolated Vo to elucidate the auto-inhibited form of Vo and its regulation of proton conductance.

Accumulation of an unprecedented 5'-deoxyadenos-4'-yl radical unmasks the kinetics of the radical-mediated C-C bond formation step in MoaA catalysis

This paper characterizes the kinetics of the radical-mediated C-C bond formation in MoaA, revealing a shunt pathway and determining the rate of the 3',8-cyclization step.

Higher seroprevalence of Entamoeba histolytica than that of HIV-1 at a voluntary counselling and testing centre in Tokyo

The paper reports higher seroprevalence of Entamoeba histolytica compared to HIV-1 and syphilis in a Tokyo VCT center, with risk factors including male sex, older age, and syphilis positivity.