A. O'Connor

Heavy metal pollution impacts soil bacterial community structure and antimicrobial resistance at the Birmingham 35th Avenue Superfund Site

This study examines how heavy metal pollution affects soil bacterial communities and antimicrobial resistance at a Superfund site, finding reduced diversity and increased AMR gene prevalence in contaminated soils.

A Universal Stress Protein upregulated by hypoxia may contribute to chronic lung colonisation and intramacrophage survival in cystic fibrosis.

This study identifies distinct roles of two upregulated universal stress proteins in Burkholderia cenocepacia during chronic CF lung infection, showing USP76 supports macrophage survival while USP92 enhances virulence.

LipidFinder 2.0: advanced informatics pipeline for lipidomics discovery applications

LipidFinder 2.0 improves lipidomics analysis with new modules for artefact filtering, isotope deletion, and FDR assessment, showing better performance than existing tools.

Metabolic dysregulation of the lysophospholipid/autotaxin axis in the chromosome 9p21 gene SNP rs10757274

The paper identifies metabolic dysregulation of lysophospholipid/autotaxin pathways linked to a CHD risk SNP, showing altered lipid metabolism and enzyme expression in multiple models.

A method of back-calculating the log odds ratio and standard error of the log odds ratio from the reported group-level risk of disease

The paper presents a method to calculate the log odds ratio and its standard error from group-level disease risk estimates, demonstrating its superiority in standard error calculation compared to existing methods.

A hierarchical Bayesian latent class mixture model with censorship for detection of linear temporal changes in antibiotic resistance

This paper develops a hierarchical Bayesian model to detect linear temporal changes in antibiotic resistance by accounting for censored MIC data and non-resistant population trends.