Author

A. O. Olaitan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:mechanistic / dynamical model· 1 Organism:mouse· 1

Frequent Co-Authors

A. Deshpande· 2 shared C. Dureja· 2 shared J. G. Hurdle· 2 shared A. J. Gonzales-Luna· 1 shared A. M. McKelvey· 1 shared C. S. Pepperell· 1 shared J. Freeman· 1 shared J. Hurdle· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

A. Deshpande

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Decoding a cryptic mechanism of metronidazole resistance among globally disseminated fluoroquinolone-resistant Clostridioides difficile

A. O. Olaitan, C. Dureja, M. Youngblom, M. A. Topf, W.-J. Shen, A. J. Gonzales-Luna, A. Deshpande, K. E. Hevener, J. Freeman, M. H. Wilcox, K. L. Palmer, K. W. Garey, C. S. Pepperell, J. G. Hurdle

This study identifies a mutation in C. difficile that causes metronidazole resistance and links it to fluoroquinolone resistance, contributing to the spread of drug-resistant strains.

bioRxiv · Sep 23, 2022Microbiology

The Ferrous Iron Transporter FeoB1 is Essential for Clostridioides difficile Toxin Production and Pathogenesis in Mice

A. Deshpande, C. Dureja, A. M. McKelvey, W. Zhao, J. T. Rutherford, A. O. Olaitan, J. Hurdle

This study shows that FeoB1 is critical for C. difficile toxin production and virulence, suggesting it as a therapeutic target for CDI.

bioRxiv · Mar 3, 2022 · PreprintMicrobiology

Ebselen Exhibits Antimicrobial Activity Against Clostridioides difficile By Disrupting Redox Associated Metabolism

R. K. R. Marreddy, A. O. Olaitan, J. May, M. Dong, J. G. Hurdle

This study shows ebselen inhibits C. difficile by disrupting redox metabolism and toxin production, with bactericidal effects beyond its previously known anti-toxin activity.

bioRxiv · Jul 27, 2020 · PreprintMicrobiology