Author

A. P. Davenport

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

E. L. Robinson· 2 shared J. J. Maguire· 2 shared R. E. Kuc· 2 shared S. Sinha· 2 shared T. L. Williams· 2 shared A. J. Butler· 1 shared A. M. Moon· 1 shared A. W. Lohse· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPharmacology & Toxicology

E. L. Robinson

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

FXR inhibition reduces ACE2 expression, SARS-CoV-2 infection and may improve COVID-19 outcome

T. Brevini, M. Maes, G. J. Webb, W. T. H. Gelson, S. Forrest, P. Mlcochova, S. Dillon, S. Varankar, M. Darvish-Damavandi, V. L. Mulcahy, R. E. Kuc, T. L. Williams, V. Galanakis, M. Vila-Gonzalez, O. C. Tysoe, , F. Sampaziotis

This study shows FXR inhibition lowers ACE2 expression, reduces SARS-CoV-2 infection, and correlates with better clinical outcomes in COVID-19.

bioRxiv · Jun 6, 2021 · PreprintMicrobiology

Human embryonic stem cell-derived cardiomyocytes express SARS-CoV-2 host entry proteins: screen to identify inhibitors of infection

T. L. Williams, M. T. Colzani, R. G. Macrae, E. L. Robinson, S. Bloor, E. J. Greenwood, J. R. Zhan, G. Strachan, R. E. Kuc, D. Nyimanu, J. J. Maguire, P. J. Lehner, S. Sinha, A. P. Davenport

The paper identifies benztropine and DX600 as inhibitors of SARS-CoV-2 infection using a screening platform with human embryonic stem cell-derived cardiomyocytes.

bioRxiv · Jan 22, 2021 · PreprintPharmacology & Toxicology

Genes Encoding ACE2, TMPRSS2 and Related Proteins Mediating SARS-CoV-2 Viral Entry are Upregulated with Age in Human Cardiomyocytes

E. L. Robinson, K. Alkass, O. Bergmann, J. J. Maguire, L. Roderick, A. P. Davenport

This study finds that genes involved in SARS-CoV-2 entry are upregulated in aged human cardiomyocytes compared to younger ones, correlating with age.

bioRxiv · Jul 7, 2020Cell Biology