Author

A. W. Lohse

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Cardon· 1 shared A. Domene· 1 shared A. Imbert· 1 shared A. J. Butler· 1 shared A. Lannes· 1 shared A. M. Moon· 1 shared A. P. Davenport· 1 shared A. Renand· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperImmunology

A. Cardon

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Author profile →

3 papers

Recent·Most cited

The immune profile of circulating autoreactive CD4 T cells is imprinted through tissue activation during autoimmune liver diseases

A. Cardon, T. Guinebretiere, C. Dong, L. Gil, S. Ado, P.-j. Gavlovsky, M. Braud, R. Danger, C. Schultheiss, A. Domene, P. Paul-Gilloteaux, C. Chevalier, L. Bernier, J.-P. Judor, C. Fourgeux, , A. Renand

This study identifies the transcriptional profile of circulating autoreactive CD4 T cells in autoimmune liver diseases and shows their functional relationship to liver-specific pathogenic clones.

bioRxiv · Mar 26, 2024Immunology

FXR inhibition reduces ACE2 expression, SARS-CoV-2 infection and may improve COVID-19 outcome

T. Brevini, M. Maes, G. J. Webb, W. T. H. Gelson, S. Forrest, P. Mlcochova, S. Dillon, S. Varankar, M. Darvish-Damavandi, V. L. Mulcahy, R. E. Kuc, T. L. Williams, V. Galanakis, M. Vila-Gonzalez, O. C. Tysoe, , F. Sampaziotis

This study shows FXR inhibition lowers ACE2 expression, reduces SARS-CoV-2 infection, and correlates with better clinical outcomes in COVID-19.

bioRxiv · Jun 6, 2021 · PreprintMicrobiology

Leukocyte-derived High-mobility group box 1 controls innate immune responses against Listeria monocytogenes.

A. Volmari, K. Foelsch, K. Yan, M. Qi, K. Bartels, S. Kondratowicz, M. Boettcher, M. Nishibori, K. Liu, R. F. Schwabe, A. W. Lohse, S. Huber, H.-W. Mittruecker, P. Huebener

This study shows that HMGB1 from leukocytes is critical for immune responses against Listeria monocytogenes, while hepatocyte HMGB1 is not essential for moderate infections but may contribute to excessive inflammation in severe cases.

bioRxiv · Oct 8, 2019 · PreprintImmunology