Author

D. R. Glass

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 6 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 8 Research Focus:cell type annotation· 7 Approach:experimental assay· 7 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Assay:flow cytometry· 2 Assay:proteomics· 2 Research Focus:spatial domain detection· 2

Frequent Co-Authors

S. C. Bendall· 7 shared L. Borges· 3 shared A. A. Calderon· 2 shared A. Baranski· 2 shared A. G. Tsai· 2 shared F. J. Hartmann· 2 shared J. P. Oliveria· 2 shared M. Angelo· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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7 shared papersImmunology

S. C. Bendall

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Unraveling human hematopoietic progenitor cell diversity through association with intrinsic regulatory factors

P. Favaro, D. R. Glass, L. Borges, R. B. Reemar, W. Reynolds, D. Ho, T. Bruce, D. Tebaykin, V. M. Scalon, I. Shestopalov, S. C. Bendall

The paper defines human HSPC subsets and differentiation trajectories using surface proteins and functional regulators, validated by epigenetic analysis and clonal assays.

bioRxiv · Aug 30, 2023 · PreprintCell Biology

A Distinct Phenotype of Polarized Memory B cell holds IgE Memory

J. F. Koenig, N. P. H. Knudsen, A. Phelps, K. Bruton, I. Hoof, G. Lund, D. D. Libera, A. Lund, L. Christensen, D. R. Glass, T. D. Walker, A. Fang, S. Waserman, M. Jordana, P. S. Andersen

The paper identifies a novel memory B cell subset, MBC2s, that holds allergen-specific IgE memory and contributes to IgE production in allergic diseases.

bioRxiv · Jan 25, 2023 · PreprintImmunology

Expression of terminal deoxynucleotidyl transferase (TdT) identifies lymphoid-primed progenitors in human bone marrow

Y. Kim, A. A. Calderon, P. Favaro, D. R. Glass, A. G. Tsai, L. Borges, W. J. Greenleaf, S. C. Bendall

The paper identifies TdT-expressing progenitors in human bone marrow that show lymphoid potential while retaining myeloid capacity, redefining the lympho-myeloid axis.

bioRxiv · Oct 30, 2022Immunology

Magnitude and kinetics of the human immune cell response associated with severe dengue progression by single-cell proteomics

M. L. Robinson, D. R. Glass, V. Duran, O. Rojas, A. M. Sanz, M. Consuegra, M. K. Sahoo, F. Hartmann, M. Bosse, R. M. G. Ramirez, N. Bueno, B. A. Pinsky, J. G. Montoya, H. Maecker, M. Cardenas, , S. Einav

The paper uses single-cell proteomics to analyze immune cell responses in severe dengue patients, identifying distinct immune dynamics compared to uncomplicated dengue.

bioRxiv · Sep 21, 2022Immunology

Human IL-10-producing B cells have diverse states induced from multiple B cell subsets

M. C. Glass, D. R. Glass, J. P. Oliveria, B. Mbiribindi, C. O. Esquivel, S. M. Krams, S. C. Bendall, O. M. Martinez

The paper identifies IL-10-producing B cells as a transient state induced from multiple B cell subsets, with unique enrichment in tolerant liver transplant recipients.

bioRxiv · Sep 1, 2021Immunology

Transition to invasive breast cancer is associated with progressive changes in the structure and composition of tumor stroma

T. Risom, D. R. Glass, C. C. Liu, B. Rivero-Gutierrez, A. Baranski, E. F. McCaffrey, N. F. Greenwald, A. C. Kagel, S. H. Strand, S. Varma, A. Kong, L. Keren, S. Srivastava, C. Zhu, Z. Khair, , M. Angelo

The paper analyzes tumor microenvironment changes from normal to invasive breast cancer using imaging and machine learning, finding coordinated shifts in stromal cell location and function.

bioRxiv · Jan 5, 2021Cancer Biology

Multiplexed Single-cell Metabolic Profiles Organize the Spectrum of Human Cytotoxic T Cells

F. J. Hartmann, D. Mrdjen, E. McCaffrey, D. R. Glass, N. F. Greenwald, A. Bharadwaj, Z. Khair, A. Baranski, R. Baskar, M. Angelo, S. C. Bendall

This study maps metabolic profiles of human cytotoxic T cells using single-cell technologies, revealing tissue-specific metabolic states and spatial metabolic neighborhoods in colorectal carcinoma.

bioRxiv · Jan 17, 2020 · PreprintImmunology

An integrated multi-omic single cell atlas to redefine human B cell memory

D. R. Glass, A. G. Tsai, J. P. Oliveria, F. J. Hartmann, S. C. Kimmey, A. A. Calderon, L. Borges, S. C. Bendall

The paper develops a multi-omic single-cell atlas of human B cells, identifying ten subsets and showing phenotype drives B cell function.

bioRxiv · Oct 13, 2019Immunology