P. S. Andersen

Pathogenic IgE-fated memory B cell responses retain functional plasticity

This study shows that blocking IL-4/IL-13 signaling can reprogram allergen-specific memory B cells from a pathogenic IgE fate to a non-pathogenic IgG2c fate.

Endogenous Staphylococcus aureus CRISPR-cas system limits phage proliferation and efficiently excises from the genome as part of the SCCmec cassette

This study shows that S. aureus CRISPR-Cas systems, located within SCCmec cassettes, limit phage proliferation but are inefficient, with phages able to escape or overload the system.

A Distinct Phenotype of Polarized Memory B cell holds IgE Memory

The paper identifies a novel memory B cell subset, MBC2s, that holds allergen-specific IgE memory and contributes to IgE production in allergic diseases.

All Staphylococcus aureus bacteraemia strains have the potential to cause infective endocarditis: results of GWAS and experimental animal studies

This study shows that all Staphylococcus aureus bacteraemia strains can cause infective endocarditis, as no genetic differences were found between IE and non-IE strains using GWAS and experimental models.

Chemical phylogenetics of the staphylococcal quorum sensing landscape

The paper maps staphylococcal quorum sensing interactions by testing over 200 AIPs against reporter strains, identifying a pan-inhibitory AIP that reduces MRSA skin infection in mice.

Demographic fluctuation of community-acquired antibiotic-resistant Staphylococcus aureus lineages: potential role of flimsy antibiotic exposure

The paper investigates how low-level antibiotic exposure influences the expansion of two CA-MRSA lineages by reversing the fitness cost of antibiotic resistance.