Author

A. Pluckthun

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

B. Dreier· 2 shared A. E. Leschziner· 1 shared A. Vieille· 1 shared C. Berge· 1 shared C. Galicia· 1 shared C. Lettl· 1 shared D. Chatterjee· 1 shared E. P. Karasmanis· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

B. Dreier

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Development of LRRK2 designed ankyrin-repeat proteins

V. Dederer, M. Sanz Murillo, E. P. Karasmanis, K. S. Hatch, D. Chatterjee, F. Preuss, K. R. Abdul Azeez, L. V. Nguyen, C. Galicia, B. Dreier, A. Pluckthun, W. Versees, S. Mathea, A. E. Leschziner, S. L. Reck-Peterson, S. Knapp

This study develops a high-affinity DARPin that binds to LRRK2's WD40 domain, improving structural analysis and revealing its role in disrupting LRRK2 filaments and Rab8A phosphorylation.

bioRxiv · Nov 14, 2023Biochemistry

Designed Ankyrin Repeat Proteins provide insights into the structure and function of CagI and are potent inhibitors of CagA translocation by the Helicobacter pylori type IV secretion system

M. Blanc, C. Lettl, J. Guerin, A. Vieille, S. Furler, S. Briand-Schumacher, B. Dreier, C. Berge, A. Pluckthun, S. Vadon-Le Goff, R. Fronzes, P. Rousselle, W. Fischer, L. TERRADOT

This study characterizes the structure and function of CagI in Helicobacter pylori's type IV secretion system and identifies DARPins that inhibit CagA translocation.

bioRxiv · Nov 8, 2022 · PreprintMicrobiology