Author

A. R. Colas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1

Frequent Co-Authors

A. Kervadec· 2 shared M. S. Yu· 2 shared A. Divakaruni· 1 shared A. Gupta· 1 shared A. N. Murphy· 1 shared A. Sacco· 1 shared C. Dondi· 1 shared C. Kwon· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCell Biology

A. Kervadec

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Author profile →

3 papers

Recent·Most cited

The nutrient sensor CRTC & Sarcalumenin / Thinman represent a new pathway in cardiac hypertrophy

C. Dondi, G. Vogler, A. Gupta, S. M. Walls, A. Kervadec, M. R. Romero, S. B. Diop, J. Goode, J. B. Thomas, A. R. Colas, R. Bodmer, M. Montminy, K. Ocorr

This study identifies CRTC and Sarcalumenin/TMN as a novel conserved pathway involved in cardiac hypertrophy through genetic and functional analyses in Drosophila and zebrafish.

bioRxiv · Oct 2, 2023 · PreprintCell Biology

Conserved Transcription Factors Control Chromatin Accessibility and Gene Expression to Maintain Cell Fate Stability and Restrict Reprogramming of Differentiated Cells

M. A. Missinato, S. A. Murphy, M. Lynott, A. Kervadec, M. S. Yu, Y.-L. Chang, S. Kannan, M. Loreti, C. Lee, P. Amatya, H. Tanaka, C.-T. Huang, P. L. Puri, C. Kwon, P. D. Adams, , A. R. Colas

This study identifies four conserved transcription factors that oppose cell fate reprogramming by controlling chromatin accessibility and gene expression, and shows their potential as therapeutic targets for regenerative medicine.

bioRxiv · Jun 28, 2021 · PreprintCell Biology

Lipid availability influences the metabolic maturation of human pluripotent stem cell-derived cardiomyocytes

H. Zhang, M. G. Badur, S. Spiering, A. Divakaruni, N. E. Meurs, M. S. Yu, A. R. Colas, A. N. Murphy, M. Mercola, C. M. Metallo

This study shows that lipid availability is critical for metabolic maturation of human pluripotent stem cell-derived cardiomyocytes, with exogenous lipid supplementation improving mitochondrial function and fatty acid oxidation.

bioRxiv · Mar 14, 2020 · PreprintCell Biology