Author

Y.-L. Chang

National Health Research Institutes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Immunology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2

Frequent Co-Authors

J. J. W. Chen· 2 shared A. Kervadec· 1 shared A. R. Colas· 1 shared A. Sacco· 1 shared C. Kwon· 1 shared C. Lee· 1 shared C.-C. Chang· 1 shared C.-S. Wu· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersPlant Biology

J. J. W. Chen

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Author profile →

4 papers

Recent·Most cited

A Single-Aliquot, Enrichment-Free Workflow for High-Throughput Plasma Proteome and N-Glycoproteome Profiling

Kun-Hao Chang, Jared S. Deyarmin, Tiara Pradita, Yi‐Ju Chen, Stephanie Samra, Gee‐Chen Chang, Chong-Jen Yu, Yi Chuang, Tabiwang N. Arrey, Hsiang-En Hsu, Yue Xuan, Peirong Huang, Kuen‐Tyng Lin, Ke-Hsin Yen, Irene-Ya Tai, , Yu‐Ju Chen

This paper introduces a single-aliquot, enrichment-free workflow for high-throughput plasma proteome and N-glycoproteome profiling, achieving deep coverage and reproducibility in a clinical setting.

bioRxiv · Nov 11, 2025 · PreprintBiochemistry

Auxin Plays a Role in the Adaptation of Rice to Anaerobic Germination and Seedling Establishment

K.-W. Lee, J. J. W. Chen, C.-S. Wu, H.-C. Chang, H.-Y. Chen, H.-H. Kuo, Y.-S. Lee, Y.-L. Chang, H.-C. Chang, S.-Y. Shiuea, Y.-C. Wu, Y. C. Ho, P.-W. Chen

This study shows that auxin accumulation under submergence inhibits rice root and leaf growth but promotes coleoptile elongation, with miR167-ARF-GH3 pathway regulating IAA levels to affect anaerobic germination tolerance.

bioRxiv · May 5, 2022Plant Biology

HLJ1 amplifies endotoxin-induced sepsis severity by promoting IL-12 heterodimerization in macrophages

W.-J. Luo, S.-L. Yu, C.-C. Chang, M.-H. Chien, K.-M. Liao, Y.-L. Chang, Y.-H. Chuang, J. J. W. Chen, P.-C. Yang, K.-Y. Su

This study shows HLJ1 promotes IL-12 heterodimerization in macrophages, worsening sepsis severity, and suggests targeting HLJ1 could treat IL-12/IFN-γ-related diseases.

bioRxiv · Jan 5, 2022Immunology

Conserved Transcription Factors Control Chromatin Accessibility and Gene Expression to Maintain Cell Fate Stability and Restrict Reprogramming of Differentiated Cells

M. A. Missinato, S. A. Murphy, M. Lynott, A. Kervadec, M. S. Yu, Y.-L. Chang, S. Kannan, M. Loreti, C. Lee, P. Amatya, H. Tanaka, C.-T. Huang, P. L. Puri, C. Kwon, P. D. Adams, , A. R. Colas

This study identifies four conserved transcription factors that oppose cell fate reprogramming by controlling chromatin accessibility and gene expression, and shows their potential as therapeutic targets for regenerative medicine.

bioRxiv · Jun 28, 2021 · PreprintCell Biology