Author

A. R. Hacker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

A. Majumdar· 1 shared C. K. Ngandu· 1 shared C. Wolberger· 1 shared D. E. Shorb· 1 shared D. P. Schmelyun· 1 shared E. Osei-Asante· 1 shared H. A. Orland· 1 shared J. G. Baer· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

A. Majumdar

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1 paper

Recent·Most cited

The ASCC2 CUE domain contacts adjacent ubiquitins to recognize K63-linked polyubiquitin

P. M. Lombardi, S. Haile, T. Rusanov, R. Rodell, R. Anoh, J. G. Baer, K. A. Burke, L. N. Gray, A. R. Hacker, K. R. Kebreau, C. K. Ngandu, H. A. Orland, E. Osei-Asante, D. P. Schmelyun, D. E. Shorb, , C. Wolberger

This study shows that the ASCC2 CUE domain binds K63-linked diubiquitin by interacting with both ubiquitins, with unique contacts to the proximal ubiquitin that are critical for ASCC2 recruitment during DNA alkylation response.

bioRxiv · Oct 17, 2021 · PreprintBiophysics