Author

A. R. Zelmer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

D. Yang· 4 shared G. J. Atkins· 4 shared L. B. Solomon· 4 shared N. J. Gunn· 3 shared K. Richter· 2 shared S. P. Kidd· 2 shared D. Muratovic· 1 shared E. Roscioli· 1 shared

Activity by Year

2023-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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4 shared papersMicrobiology

D. Yang

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Beyond the Colony-Forming-Unit: Rapid Bacterial Evaluation in Osteomyelitis

Q. Sun, K. Huynh, D. Muratovic, N. J. Gunn, A. R. Zelmer, L. B. Solomon, G. J. Atkins, D. Yang

This study demonstrates the discrepancy between colony-forming-unit and bacterial genome copy number in osteomyelitis and proposes an improved workflow for bacterial burden quantification in clinical specimens.

eLife · Jun 24, 2024Peer-reviewedMicrobiology

Antibiotics at Clinical Concentrations Show Limited Effectivity Against Acute and Chronic Intracellular S. aureus Infections in Osteocytes

A. R. Zelmer, D. Yang, N. J. Gunn, L. B. Solomon, R. Nelson, S. P. Kidd, K. Richter, G. J. Atkins

This study evaluates the effectiveness of antibiotics against intracellular S. aureus infections in osteocytes, finding limited efficacy even at high concentrations.

bioRxiv · Dec 17, 2023 · PreprintMicrobiology

Staphylococcus aureus Persistence in Osteocytes: Weathering the Storm of Antibiotics and Autophagy/Xenophagy

N. J. Gunn, A. R. Zelmer, S. P. Kidd, L. B. Solomon, D. Yang, E. Roscioli, G. J. Atkins

This study investigates how antibiotics and autophagy modulation affect intracellular Staphylococcus aureus persistence in osteocytes, finding that antibiotics inhibit autophagy but do not clear bacterial DNA.

bioRxiv · Oct 27, 2023 · PreprintMicrobiology

Culture of Saos-2 cells under hypoxic conditions stimulates rapid differentiation to an osteocyte-like stage

A. R. Zelmer, Y. Starczak, L. B. Solomon, K. Richter, D. Yang, G. J. Atkins

This study shows that culturing Saos-2 cells under hypoxic conditions accelerates their differentiation into osteocyte-like cells within 14 days.

bioRxiv · Apr 23, 2023 · PreprintCell Biology